Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 9/20 | 0.43 |
| ▸ | FNTB | P49356 | 9/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078136 | 0.79 | MMP2 (0.58) | FNTAFNTBMTNR1B | |
| SCHEMBL7080988 | 0.72 | ITGB3 (0.44) | CASRITGB3ITGAV | |
| SCHEMBL7137876 | 0.72 | CCR4 (0.44) | FNTAFNTBMAPK14 | |
| SCHEMBL7078388 | 0.72 | NAMPT (0.44) | CASRITGB3ITGAV | |
| SCHEMBL7162277 | 0.71 | FNTA (0.46) | FNTAFNTBMMP13 | |
| SCHEMBL7162281 | 0.71 | FNTA (0.46) | FNTAFNTBMMP13 | |
| SCHEMBL8909238 | 0.70 | GABBR2 (0.56) | — | |
| SCHEMBL7078041 | 0.70 | RORC (0.47) | — | |
| SCHEMBL6772429 | 0.69 | KMT2A (0.47) | FNTAFNTBFFAR1 | |
| SCHEMBL7130423 | 0.67 | RORC (0.44) | FNTAFNTBMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |