SCHEMBL7077904

SCHEMBL7077904

COC(=O)CC[C@H](NC(=O)c1ccc(NCC2CNc3nc(N)[nH]c(=O)c3N2)cc1)C(=O)O

nearest known ligand 0.85

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SOST Q9BQB4 1/20 0.85
FPGS Q05932 2/20 0.84
GART P22102 5/20 0.64
DHFR P00374 1/20 0.58
ATIC P31939 4/20 0.56
MTHFD1 P11586 2/20 0.56
LMNA P02545 1/20 0.49
MTHFD2 P13995 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20509041 1.00 SOST (0.85) SOSTFPGSGARTDHFRATIC
SCHEMBL27903149 1.00 SOST (0.85) SOSTFPGSGARTDHFRATIC
SCHEMBL133543 1.00 SOST (0.85) SOSTFPGSGARTDHFRATIC
SCHEMBL7076983 1.00 SOST (0.85) SOSTFPGSGARTDHFRATIC
SCHEMBL28206347 0.99 SOST (0.84) SOSTFPGSGARTDHFRATIC
SCHEMBL27284124 0.99 SOST (0.84) SOSTFPGSGARTDHFRATIC
Phosphoric Acid SCHEMBL28313723 0.98 SOST (0.82) SOSTFPGSGARTDHFRATIC
Tetrahydrofolate SCHEMBL27798266 0.98 SOST (0.90) SOSTFPGSGARTDHFRATIC
Glycine SCHEMBL27746532 0.97 SOST (0.83) SOSTFPGSGARTDHFRATIC
Butyric Acid SCHEMBL28187742 0.94 SOST (0.76) SOSTFPGSGARTDHFRATIC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4687872-A1 ORAL ACTIVE INGREDIENT COMBINATION CONTAINING L-ARGININE, L-CITRULLINE, SELENITE AND WATER-SOLUBLE BORON RFB HealthCare GmbH (DE) 2026-02-11 EP claimed
WO-2024208506-A1 ORAL ACTIVE INGREDIENT COMBINATION CONTAINING L-ARGININE, L-CITRULLINE, SELENITE AND WATER-SOLUBLE BORON RFB HEALTHCARE GMBH (DE) 2024-10-10 WO claimed
EP-4687872-A1 ORAL ACTIVE INGREDIENT COMBINATION CONTAINING L-ARGININE, L-CITRULLINE, SELENITE AND WATER-SOLUBLE BORON RFB HealthCare GmbH (DE) 2026-02-11 EP disclosed
US-12516357-B1 Modified host cells for high efficiency production of vanillin Amyris, Inc. (US) 2026-01-06 US disclosed
EP-4514362-A1 NICOTINAMIDE RIBOSIDE DOSAGE REGIMEN FOR TREATING PARKINSON'S DISEASE VESTLANDETS INNOVASJONSSELSKAP AS (VIS) (NO) 2025-03-05 EP disclosed
US-20240343969-A1 METHOD FOR RECYCLING AN LED PARIS SCIENCES ET LETTRES (FR) 2024-10-17 US disclosed
WO-2024208506-A1 ORAL ACTIVE INGREDIENT COMBINATION CONTAINING L-ARGININE, L-CITRULLINE, SELENITE AND WATER-SOLUBLE BORON RFB HEALTHCARE GMBH (DE) 2024-10-10 WO disclosed
US-20240132677-A1 SPRAY-DRYING OF SOLID EPOXY OR PHENOXY RESINS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2024-04-25 US disclosed
EP-3359138-B1 DIETARY SUPPLEMENTATION TO ACHIEVE OXY-REDOX HOMEOSTASIS AND EPIGENETIC STABILITY PARTHENOGEN SAGL (CH) 2024-04-24 EP disclosed
US-11872230-B2 Method of treating a methionine-dependent cancer AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2024-01-16 US disclosed
US-11851390-B2 Reaction of glycoladehyde TAMINCO BVBA 2023-12-26 US disclosed
EP-4240538-A1 SPRAY-DRYING OF SOLID EPOXY OR PHENOXY RESINS Huntsman Advanced Materials Americas LLC (US) 2023-09-13 EP disclosed
US-20230114628-A1 Prenatal Dosage Forms, Methods of Administration and Kits Thereof ELLEMENT INC. 2023-04-13 US disclosed
WO-2023007088-A1 FOOD SUPPLEMENT FOR COMBATING FEMALE AND MALE INFERTILITY NURIBIOL (FR) 2023-02-02 WO disclosed
US-20220280520-A1 METHOD OF TREATING A METHIONINE-DEPENDENT CANCER AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2022-09-08 US disclosed
US-11376256-B2 Method of treating a methionine-dependent cancer AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2022-07-05 US disclosed
US-20220151937-A1 COMPOSITION FOR NAP PROMOTION NapJitsu, Inc. 2022-05-19 US disclosed
WO-2022098927-A1 SPRAY-DRYING OF SOLID EPOXY OR PHENOXY RESINS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2022-05-12 WO disclosed
US-20030148991-A1 Use of at least one lipoic acid, of a physiologically acceptable derivative and/or salt thereof and at least one C1 donor for producing formulation for C1 donor-assisted therapy of central nervous system disorders BASF AKTIENGESELLSCHAFT (DE) 2003-08-07 US disclosed
WO-2001002600-A9 DETECTION OF ANALYTES USING ATTENUATED ENZYMES GEN ATOMICS (US) 2002-07-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030148991-A1 Use of at least one lipoic acid, of a physiologically acceptable derivative and/or salt thereof and at least one C1 donor for producing formulation for C1 donor-assisted therapy of central nervous system disorders AMD1, MAT1A, C1S SOST 3540/4885FPGS 259/4885GART 108/4885
US-11851390-B2 Reaction of glycoladehyde ADH1A, ADH1C, GRHPR SOST 2511/4885FPGS 690/4885GART 236/4885
US-11872230-B2 Method of treating a methionine-dependent cancer MGMT, BHMT2, MTR SOST 4784/4885FPGS 131/4885GART 2838/4885
US-11376256-B2 Method of treating a methionine-dependent cancer MGMT, BHMT2, MTR SOST 4650/4885FPGS 122/4885GART 2475/4885
US-20220280520-A1 METHOD OF TREATING A METHIONINE-DEPENDENT CANCER MGMT, BHMT2, MTR SOST 4784/4885FPGS 131/4885GART 2838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.