Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 16/20 | 0.50 |
| ▸ | FNTB | P49356 | 16/20 | 0.50 |
| ▸ | MET | P08581 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078136 | 0.78 | MMP2 (0.58) | FNTAFNTB | |
| SCHEMBL6468349 | 0.75 | PGR (0.62) | MET | |
| SCHEMBL7077840 | 0.71 | GABBR2 (0.49) | FNTAFNTB | |
| SCHEMBL7077860 | 0.71 | GABBR2 (0.49) | FNTAFNTB | |
| SCHEMBL7078041 | 0.69 | RORC (0.47) | — | |
| SCHEMBL7162281 | 0.69 | FNTA (0.46) | FNTAFNTB | |
| SCHEMBL7162277 | 0.69 | FNTA (0.46) | FNTAFNTB | |
| SCHEMBL2453521 | 0.68 | NAMPT (0.51) | — | |
| SCHEMBL7130818 | 0.68 | MAPT (0.52) | FNTAFNTB | |
| SCHEMBL7073837 | 0.68 | FNTA (0.52) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |