Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL7092453

CSc1cccc([O-])c1.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Al+3]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
GPR3 P46089 2/20 0.40
HPGD P15428 2/20 0.38
GAA P10253 2/20 0.38
PTGS2 P35354 1/20 0.38
KCNH2 Q12809 6/20 0.35
ACHE P22303 1/20 0.35
ALDH1A1 P00352 1/20 0.35
ESR1 P03372 1/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HCRTR1 O43613 1/20 0.34
HCRTR2 O43614 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL7092452 0.89 L3MBTL1 (0.40) L3MBTL1HPGDGAAPTGS2ALDH1A1
SCHEMBL10953615 0.78 MEN1 (0.39) L3MBTL1HPGDGAAALDH1A1MEN1
Trifluoromethanesulfonic Acid SCHEMBL7089263 0.76 GPR3 (0.44) GPR3PTGS2KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL7089713 0.75 ACHE (0.42) L3MBTL1GPR3KCNH2ACHEALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL7089027 0.75 GPR3 (0.43) GPR3KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL7086264 0.74 GPR3 (0.40) GPR3PTGS2KCNH2ACHEALDH1A1
1-Hydroxy-3-Methoxybenzene SCHEMBL7085847 0.74 KCNH2 (0.49) GPR3PTGS2KCNH2ACHEALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL6560666 0.73 GPR3 (0.57) GPR3KCNH2ACHEALDH1A1TSHR
Trifluoromethanesulfonic Acid SCHEMBL7213150 0.72 ACHE (0.40) L3MBTL1GPR3KCNH2ACHEALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL6323261 0.67 ALDH1A1 (0.37) GPR3HPGDGAAPTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6624321-B2 Metathesis ring-opening polymerization of cyclic ethers in the presence of catalysts such as aluminum bis(trifluoromethane-sulfonate) phenolate BAYER AKTIENGESELLSCHAFT (DE) 2003-09-23 US disclosed
US-20030097026-A1 Process for the preparation of polyether polyols DENNINGER UWE (DE) 2003-05-22 US disclosed
US-6492565-B2 USING ALKYLENE OXIDE IN PRESENCE OF LEWIS ACID CATALYST BAYER AKTIENGESELLSCHAFT (DE) 2002-12-10 US disclosed
US-20010053866-A1 Process for the preparation of polyether polyols BAYER AKTIENGESELLSCHAFT (DE) 2001-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030097026-A1 Process for the preparation of polyether polyols PCBP1, FHIT, PUF60 L3MBTL1 3214/4885GPR3 3548/4885HPGD 2755/4885
US-20010053866-A1 Process for the preparation of polyether polyols PCBP1, FHIT, PUF60 L3MBTL1 3214/4885GPR3 3548/4885HPGD 2755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.