Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL74504 | 0.84 | ALDH1A1 (0.39) | ALDH1A1MAPK1TSHRGPR3SMN1; SMN2 | |
| Trifluoromethanesulfonic Acid SCHEMBL3139918 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPK1TSHRGPR3SMN1; SMN2 | |
| Trifluoromethanesulfonic Acid SCHEMBL562050 | 0.80 | GPR3 (0.43) | ALDH1A1GPR3SMN1; SMN2KMT2AMEN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL4182001 | 0.79 | KCNH2 (0.43) | ALDH1A1GPR3GAAESR1LMNA | |
| Trifluoromethanesulfonic Acid SCHEMBL30536270 | 0.79 | ACHE (0.43) | ALDH1A1GPR3KMT2AMEN1PTGS2 | |
| Trifluoromethanesulfonic Acid SCHEMBL36457 | 0.78 | GPR3 (0.47) | GPR3 | |
| Trifluoromethanesulfonic Acid SCHEMBL30925713 | 0.77 | ENPP2 (0.44) | GPR3KMT2AGAAESR1LMNA | |
| Trifluoromethanesulfonic Acid SCHEMBL30536277 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPK1TSHRGPR3SMN1; SMN2 | |
| Trifluoromethanesulfonic Acid SCHEMBL5146818 | 0.76 | KCNH2 (0.46) | KMT2AGAA | |
| Trifluoromethanesulfonic Acid SCHEMBL30417272 | 0.76 | PTGS2 (0.38) | ALDH1A1MAPK1GPR3PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050258398-A1 | Dithia-s-indacene derivative | TAKASAGO INTERNATIONAL CORPORATION | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050258398-A1 | Dithia-s-indacene derivative | DDB1, XDH, TXNL1 | ALDH1A1 1916/4885MAPK1 687/4885TSHR 1114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.