Sugi Predict

Sugi Predict / Compounds / SCHEMBL709544

SCHEMBL709544

SCHEMBL709544

CCOC(=O)c1ncc(C(F)(F)F)cc1Cl

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.60
▸ ALDH1A1 P00352 6/20 0.58
▸ HPGD P15428 2/20 0.57
▸ KMT2A Q03164 5/20 0.56
▸ MEN1 O00255 4/20 0.56
▸ MAPT P10636 1/20 0.55
▸ GLA P06280 1/20 0.53
▸ MAPK1 P28482 1/20 0.52
▸ RECQL P46063 2/20 0.51
▸ SMN1; SMN2 Q16637 1/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ LMNA P02545 2/20 0.50
▸ GAA P10253 2/20 0.49
▸ POLB P06746 1/20 0.49
▸ CYP1A2 P05177 1/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ CYP2C19 P33261 1/20 0.48
▸ MRGPRX4 Q96LA9 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30453140 1.00 L3MBTL1 (0.60) L3MBTL1ALDH1A1HPGDKMT2AMEN1
SCHEMBL31214261 0.90 L3MBTL1 (0.49) L3MBTL1ALDH1A1HPGDKMT2AMEN1
SCHEMBL25963292 0.89 ALDH1A1 (0.53) L3MBTL1ALDH1A1HPGDKMT2AMEN1
SCHEMBL7787959 0.87 AGBL2 (0.51) L3MBTL1ALDH1A1HPGDKMT2AMEN1
SCHEMBL3685180 0.84 L3MBTL1 (0.50) L3MBTL1ALDH1A1HPGDKMT2AMEN1
SCHEMBL4125681 0.84 MAPK1 (0.59) L3MBTL1ALDH1A1HPGDKMT2AMEN1
SCHEMBL31338969 0.84 MAPK1 (0.59) L3MBTL1ALDH1A1HPGDKMT2AMEN1
SCHEMBL16456041 0.83 CFTR (0.53) L3MBTL1ALDH1A1HPGDKMT2AMEN1
SCHEMBL709666 0.83 L3MBTL1 (0.47) L3MBTL1ALDH1A1HPGDKMT2AMEN1
SCHEMBL30861678 0.83 ALDH1A1 (0.54) L3MBTL1ALDH1A1HPGDKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-05-13 — — US disclosed
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-04-08 — — US disclosed
US-12134616-B2 Tricyclic pesticidal compounds BASF SE (DE) 2024-11-05 — — US disclosed
US-20240360155-A1 Benzodiazepine Derivatives as RSV Inhibitors ENANTA PHARM INC (US) 2024-10-31 — — US disclosed
US-20240360117-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARM INC (US) 2024-10-31 — — US disclosed
CN-112867714-B Pesticidal tricyclic compounds 巴斯夫欧洲公司 2024-06-11 — — CN disclosed
US-11952389-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2024-04-09 — — US disclosed
CN-113710276-B Benzodiazepine derivatives as RSV inhibitors 英安塔制药有限公司 2024-03-29 — — CN disclosed
EP-3687543-B1 COMBINATIONS OF PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARM INC (US) 2024-03-20 — — EP disclosed
US-11935803-B2 Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-03-19 — — US disclosed
US-6274536-B1 CROPS, AGRICULTURE; PRE- AND POSTEMERGENCE SYNGENTA CROP PROTECTION, INC. 2001-08-14 — — US disclosed
US-6204221-B1 Herbicides SYNGENTA CROP PROTECTION, INC. 2001-03-20 — — US disclosed
US-6169183-B1 REACTING 2,3-DIHALOPYRIDINE WITH CARBON MONOXIDE AND ALKANOL IN PRESENCE OF WEAK BASE AND COMPLEX OF PALLADIUM WITH SPECIFIED BIS(DIPHENYLPHOSPHINE), WHEREIN REACTION IS STOPPED AS SOON AS MAXIMUM CONCENTRATION OF ESTER IS ACHIEVED LONZA, LTD. (CH) 2001-01-02 — — US disclosed
CN-1250446-A Pyrazole derivatives as herbicides NOVARTIS AG (CH) 2000-04-12 — — CN disclosed
EP-0966461-A1 PYRAZOLE DERIVATIVES AS HERBICIDES Novartis AG (CH) 1999-12-29 — — EP disclosed
CN-1237166-A Pyrazole derivatives useful as herbicides NOVARTIS AG (CH) 1999-12-01 — — CN disclosed
EP-0941222-A2 PYRAZOLE DERIVATIVES USEFUL AS HERBICIDES Novartis AG (CH) 1999-09-15 — — EP disclosed
WO-1998042698-A1 PYRAZOLE DERIVATIVES AS HERBICIDES NOVARTIS AG (CH) 1998-10-01 — — WO disclosed
WO-1998021199-A2 PYRAZOLE DERIVATIVES USEFUL AS HERBICIDES NOVARTIS AG (CH) 1998-05-22 — — WO disclosed
US-4995902-A Novel herbicides CIBA-GEIGY CORPORATION (US) 1991-02-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360155-A1 Benzodiazepine Derivatives as RSV Inhibitors GABRA5, GABRA1, GABBR2 L3MBTL1 4773/4885ALDH1A1 621/4885HPGD 869/4885
US-11952389-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 L3MBTL1 4773/4885ALDH1A1 621/4885HPGD 869/4885
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 L3MBTL1 4773/4885ALDH1A1 621/4885HPGD 869/4885
US-20240360117-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS GABRA5, GABRA1, GABBR2 L3MBTL1 4773/4885ALDH1A1 621/4885HPGD 869/4885
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ACE, ACE2, SPCS3 L3MBTL1 4863/4885ALDH1A1 4172/4885HPGD 2245/4885
US-12134616-B2 Tricyclic pesticidal compounds DDT, ACHE, PFAS L3MBTL1 1778/4885ALDH1A1 813/4885HPGD 2590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.