Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 12/20 | 0.57 |
| ▸ | CA2 known ✓ | P00918 | 12/20 | 0.57 |
| ▸ | CA12 known ✓ | O43570 | 9/20 | 0.57 |
| ▸ | CA9 | Q16790 | 12/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30396962 | 0.91 | CA1 (0.55) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL30880453 | 0.90 | CA1 (0.44) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL8582932 | 0.90 | CA1 (0.44) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL8318080 | 0.87 | CA1 (0.48) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL8553335 | 0.85 | CA1 (0.53) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL8626732 | 0.80 | CA1 (0.42) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL29351875 | 0.80 | CA1 (0.55) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL344719 | 0.80 | CA1 (0.55) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL29404788 | 0.80 | CA1 (0.55) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL3144480 | 0.80 | CA1 (0.55) | CA1CA2CA9CA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003089562-A1 | POUCHED CLEANING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2003-10-30 | — | — | WO | disclosed |
| WO-2002094974-A1 | POUCHED COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2002-11-28 | — | — | WO | disclosed |
| WO-2002094975-A1 | POUCHED COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2002-11-28 | — | — | WO | disclosed |
| EP-0929622-A4 | DETERGENT COMPOSITIONS | PROCTER & GAMBLE (US) | 2000-01-05 | — | — | EP | disclosed |
| EP-0929622-A1 | DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1999-07-21 | — | — | EP | disclosed |
| EP-0782558-A4 | DETERGENT COMPOSITIONS | PROCTER & GAMBLE (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1998013448-A1 | DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-04-02 | — | — | WO | disclosed |
| WO-1998000491-A1 | DETERGENT COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1998-01-08 | — | — | WO | disclosed |
| EP-0782558-A1 | DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-09 | — | — | EP | disclosed |
| EP-0763084-A1 | DYE TRANSFER INHIBITING COMPOSITIONS CONTAINING OLEOYL SARCOSINATE | THE PROCTER & GAMBLE COMPANY (US) | 1997-03-19 | — | — | EP | disclosed |
| WO-1996009273-A1 | DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-03-28 | — | — | WO | disclosed |
| WO-1995033026-A1 | DYE TRANSFER INHIBITING COMPOSITIONS CONTAINING OLEOYL SARCOSINATE | THE PROCTER & GAMBLE COMPANY (US) | 1995-12-07 | — | — | WO | disclosed |