Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL5760494 | 0.91 | MEN1 (0.37) | MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL5022370 | 0.79 | ALDH1A1 (0.40) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| SCHEMBL23269 | 0.79 | CA5A (0.39) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| SCHEMBL27433721 | 0.79 | CA5A (0.39) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| Ammonia Solution, Strong SCHEMBL5760496 | 0.76 | CA5A (0.36) | TSHR | |
| Water SCHEMBL1614964 | 0.76 | CA5A (0.36) | TSHR | |
| SCHEMBL2571875 | 0.76 | CA5A (0.36) | TSHR | |
| SCHEMBL14974666 | 0.76 | CA5A (0.36) | TSHR | |
| SCHEMBL29170918 | 0.76 | CA5A (0.36) | TSHR | |
| SCHEMBL16756653 | 0.76 | CA5A (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776668-B1 | Process for the removal of aromatic compounds from solutions | AVENTIS BEHRING GMBH (DE) | 2003-09-24 | — | — | EP | claimed |
| US-5883256-A | CLEANING FOR VIRAL AGENTS | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | claimed |
| US-5883256-A | CLEANING FOR VIRAL AGENTS | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |