Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10060650 | 0.98 | TSHR (0.46) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4860614 | 0.82 | LMNA (0.37) | TSHRALDH1A1 | |
| SCHEMBL13636831 | 0.80 | THRB (0.39) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL3742820 | 0.75 | — | — | |
| SCHEMBL10358044 | 0.75 | — | — | |
| SCHEMBL5081197 | 0.75 | LMNA (0.32) | TSHRALDH1A1HSD17B10 | |
| SCHEMBL10358045 | 0.75 | — | — | |
| SCHEMBL4860659 | 0.75 | LMNA (0.32) | TSHRALDH1A1HSD17B10 | |
| SCHEMBL5081721 | 0.75 | LMNA (0.32) | TSHRALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL6856682 | 0.75 | TSHR (0.36) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624048-B2 | Photochromic cyclic compound and curable composition containing the photochromic cyclic compound | TOKUYAMA CORPORATION (JP) | 2026-05-12 | — | — | US | disclosed |
| US-12595408-B2 | Photochromic compound, naphthol derivative, curable composition, optical article, lens, and eyeglasses | TOKUYAMA CORPORATION (JP) | 2026-04-07 | — | — | US | disclosed |
| US-12570894-B2 | Photochromic compound and curable composition containing the photochromic compound | TOKUYAMA CORPORATION (JP) | 2026-03-10 | — | — | US | disclosed |
| EP-4692072-A1 | PHOTOCHROMIC COMPOUND, PROPARGYL ALCOHOL COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND SPECTACLES | TOKUYAMA CORPORATION (JP) | 2026-02-11 | — | — | EP | disclosed |
| EP-4692071-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS | TOKUYAMA CORPORATION (JP) | 2026-02-11 | — | — | EP | disclosed |
| EP-3779572-B1 | OPTICAL ARTICLE | HOYA LENS THAILAND LTD (TH) | 2025-11-19 | — | — | EP | disclosed |
| US-20250122163-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2025-04-17 | — | — | US | disclosed |
| WO-2025070122-A1 | PHOTOCHROMIC COMPOSITION, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2025-04-03 | — | — | WO | disclosed |
| US-20250101294-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2025-03-27 | — | — | US | disclosed |
| WO-2025057814-A1 | PHOTOCHROMIC COMPOSITION, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2025-03-20 | — | — | WO | disclosed |
| EP-0900798-A1 | FULGIMIDE COMPOUNDS, USE OF THEM, AND COMPOSITIONS CONTAINING THE SAME | TOKUYAMA CORPORATION (JP) | 1999-03-10 | — | — | EP | disclosed |
| US-5808100-A | DURABILITY | TOKUYAMA CORPORATION (JP) | 1998-09-15 | — | — | US | disclosed |
| US-5708063-A | REVERSABLE COLOR COMPOUNDS | TOKUYAMA CORPORATION (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0778276-A1 | Photochromic chromene derivatives | TOKUYAMA CORPORATION (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5631382-A | PHOTOCHROMIC LENSES | TOKUYAMA CORPORATION (JP) | 1997-05-20 | — | — | US | disclosed |
| EP-0696582-A1 | Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides | TOKUYAMA CORPORATION (JP) | 1996-02-14 | — | — | EP | disclosed |
| EP-0629626-A2 | Cyclopropyl-substituted spiro-photochromic compounds | TOKUYAMA CORPORATION (JP) | 1994-12-21 | — | — | EP | disclosed |
| EP-0629656-A2 | Photochromic article | NIKON CORPORATION (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5246989-A | PHOTOCHROMIC COMPOUND, COMPOSITION AND USE THEREOF | TOKUYAMA SODA KABISHIKI KAISHA (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0449669-A1 | Photochromic compound, composition and use thereof | TOKUYAMA CORPORATION (JP) | 1991-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595408-B2 | Photochromic compound, naphthol derivative, curable composition, optical article, lens, and eyeglasses | CRYAA, CRYZ, CRY2 | TSHR 2387/4885ALDH1A1 185/4885TP53 2891/4885 |
| US-20250122163-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | CCNE1, NAP1L1, CRYZ | TSHR 2592/4885ALDH1A1 1010/4885TP53 1497/4885 |
| US-12570894-B2 | Photochromic compound and curable composition containing the photochromic compound | SMC4, HBG2, SPTBN1 | TSHR 3786/4885ALDH1A1 2699/4885TP53 2217/4885 |
| US-20250101294-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | NAP1L1, CRYAA, CRYZ | TSHR 4072/4885ALDH1A1 224/4885TP53 2920/4885 |
| US-12624048-B2 | Photochromic cyclic compound and curable composition containing the photochromic cyclic compound | CCNL2, CRY2, CRY1 | TSHR 2358/4885ALDH1A1 1492/4885TP53 4056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.