Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 7/20 | 0.41 |
| ▸ | MMP2 | P08253 | 7/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 4/20 | 0.40 |
| ▸ | MMP14 | P50281 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 5/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940649 | 0.92 | MMP2 (0.46) | MMP9MMP2MMP8MMP13MMP14 | |
| SCHEMBL941821 | 0.89 | MMP2 (0.49) | MMP9MMP2MMP8MMP13MMP14 | |
| SCHEMBL14085484 | 0.75 | ALDH1A1 (0.46) | MMP9MMP2MMP8MMP13MMP14 | |
| SCHEMBL6841100 | 0.71 | ALDH1A1 (0.46) | MMP9MMP2MMP8SMN1; SMN2NPSR1 | |
| SCHEMBL12416111 | 0.70 | SMN1; SMN2 (0.40) | MMP9MMP2MMP13MMP14MMP12 | |
| SCHEMBL12378830 | 0.70 | ADAMTS5 (0.42) | MMP2MMP13MMP14MMP12SMN1; SMN2 | |
| SCHEMBL6210406 | 0.69 | ADAMTS5 (0.43) | MMP2MMP13MMP14MMP12SMN1; SMN2 | |
| SCHEMBL12378821 | 0.67 | ADAMTS5 (0.43) | MMP9MMP2MMP13MMP14MMP12 | |
| SCHEMBL6879272 | 0.67 | MMP14 (0.38) | MMP9MMP2MMP8MMP13MMP14 | |
| SCHEMBL7199008 | 0.67 | MMP14 (0.38) | MMP9MMP2MMP8MMP13MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127528-A1 | Metalloproteinase inhibitors | ASTRAZENECA AB (SE) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127528-A1 | Metalloproteinase inhibitors | MMP9, MMP10, MMP3 | MMP9 1/4885MMP2 11/4885MMP8 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.