Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 14/20 | 0.74 |
| ▸ | RAB9A | P51151 | 14/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.74 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.62 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 7/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.59 |
| ▸ | RELA | Q04206 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515308 | 0.91 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2NOTUMATAD2 | |
| SCHEMBL11635661 | 0.88 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2NOTUMATAD2 | |
| SCHEMBL46426 | 0.86 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2NOTUMATAD2 | |
| SCHEMBL4343181 | 0.84 | NPC1 (0.94) | NPC1RAB9ASMN1; SMN2NOTUMATAD2 | |
| SCHEMBL6498685 | 0.82 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2NOTUMATAD2 | |
| SCHEMBL46424 | 0.81 | NPC1 (0.90) | NPC1RAB9ASMN1; SMN2NOTUMATAD2 | |
| SCHEMBL22858502 | 0.81 | NPC1 (0.90) | NPC1RAB9ASMN1; SMN2NOTUMATAD2 | |
| SCHEMBL74999 | 0.81 | NPC1 (0.90) | NPC1RAB9ASMN1; SMN2NOTUMATAD2 | |
| SCHEMBL522555 | 0.81 | NPC1 (0.90) | NPC1RAB9ASMN1; SMN2NOTUMATAD2 | |
| SCHEMBL715720 | 0.80 | SMN1; SMN2 (0.69) | NPC1RAB9ASMN1; SMN2NOTUMATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183287-B1 | ORGANIC SEMICONDUCTORS BASED ON STATISTICAL COPOLYMERS | QINETIQ LTD (GB) | 2005-01-26 | — | — | EP | claimed |
| US-6642332-B1 | N-heterocyclic hole and electron transporting groups linked to vinyl group of addition polymers; electronic work function; charge carrier mobility; controlled emmission; storage stability; film-forming; light emitting diode | QINETIQ LIMITED (GB) | 2003-11-04 | — | — | US | claimed |
| US-20230312491-A1 | N-SUBSTITUTED 4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)ANILINE FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2023-10-05 | — | — | US | disclosed |
| EP-4251614-A1 | N-SUBSTITUTED 4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)ANILINE FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. Hoffmann-La Roche AG (CH) | 2023-10-04 | — | — | EP | disclosed |
| WO-2022112139-A1 | N-SUBSTITUTED 4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)ANILINE FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2022-06-02 | — | — | WO | disclosed |
| US-20220059782-A1 | PHOSPHORESCENT PtM2 (M=Cu,Ag,Au) COMPLEX AND ORGANIC LIGHT-EMITTING DIODE THEREOF | FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER, CHINESE ACADEMY OF SCIENCES (CN) | 2022-02-24 | — | — | US | disclosed |
| CN-111909222-B | Phosphorescent PtM2(M = Cu, Ag, Au) complex and organic light emitting diode thereof | 中国科学院福建物质结构研究所 | 2022-02-18 | — | — | CN | disclosed |
| CN-111909222-A | Phosphorescent PtM2(M = Cu, Ag, Au) complex and organic light emitting diode thereof | 中国科学院福建物质结构研究所 | 2020-11-10 | — | — | CN | disclosed |
| US-10243151-B2 | Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2019-03-26 | — | — | US | disclosed |
| US-20170250352-A1 | Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2017-08-31 | — | — | US | disclosed |
| US-9620723-B2 | Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2017-04-11 | — | — | US | disclosed |
| CN-103044269-B | Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LAB | 2014-05-07 | — | — | CN | disclosed |
| US-20130112961-A1 | Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2013-05-09 | — | — | US | disclosed |
| US-8343639-B2 | Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2013-01-01 | — | — | US | disclosed |
| US-20120049768-A1 | Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-03-01 | — | — | US | disclosed |
| EP-2321862-A1 | ORGANIC SEMICONDUCTOR MATERIAL AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, LIGHTING SYSTEM, AND ELECTRONIC DEVICE USING THE SAME | Semiconductor Energy Laboratory Co, Ltd. (JP) | 2011-05-18 | — | — | EP | disclosed |
| CN-101851216-A | Oxadiazole derivative, and electronic device and lighting device using same | SEMICONDUCTOR ENERGY LAB | 2010-10-06 | — | — | CN | disclosed |
| WO-2010027004-A1 | ORGANIC SEMICONDUCTOR MATERIAL AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, LIGHTING SYSTEM, AND ELECTRONIC DEVICE USING THE SAME | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2010-03-11 | — | — | WO | disclosed |
| US-20100060155-A1 | Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2010-03-11 | — | — | US | disclosed |
| EP-1183287-B1 | ORGANIC SEMICONDUCTORS BASED ON STATISTICAL COPOLYMERS | QINETIQ LTD (GB) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10243151-B2 | Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same | OXA1L, BECN1, MAP1LC3A | NPC1 4299/4885RAB9A 3158/4885SMN1; SMN2 3015/4885 |
| US-20170250352-A1 | Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same | OXA1L, BECN1, MAP1LC3A | NPC1 4299/4885RAB9A 3158/4885SMN1; SMN2 3015/4885 |
| US-20100060155-A1 | Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same | OXA1L, BECN1, MAP1LC3A | NPC1 4299/4885RAB9A 3158/4885SMN1; SMN2 3015/4885 |
| US-20120049768-A1 | Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound | AFF2, MAPRE2, AFF4 | NPC1 2154/4885RAB9A 440/4885SMN1; SMN2 4102/4885 |
| US-20130112961-A1 | Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same | OXA1L, BECN1, MAP1LC3A | NPC1 4299/4885RAB9A 3158/4885SMN1; SMN2 3015/4885 |
| US-20220059782-A1 | PHOSPHORESCENT PtM2 (M=Cu,Ag,Au) COMPLEX AND ORGANIC LIGHT-EMITTING DIODE THEREOF | ITGA2, METTL3, EIF2A | NPC1 4483/4885RAB9A 4068/4885SMN1; SMN2 4235/4885 |
| US-20230312491-A1 | N-SUBSTITUTED 4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)ANILINE FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | SLC10A1, HAVCR2, CYP4B1 | NPC1 106/4885RAB9A 2865/4885SMN1; SMN2 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.