Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30543794 | 0.81 | LMNA (0.48) | GAAMMP2MMP3MMP9MMP8 | |
| SCHEMBL14198379 | 0.80 | TSHR (0.63) | NPY2RMGLLTSHRGAAALDH1A1 | |
| SCHEMBL4709679 | 0.80 | PRMT5 (0.64) | GAAALDH1A1PRMT5WDR77LMNA | |
| SCHEMBL12469109 | 0.80 | ALDH1A1 (0.47) | MMP2MMP3MMP9MMP8MMP13 | |
| SCHEMBL5770204 | 0.80 | CTSK (0.44) | NPY2RTSHRMMP2MMP3MMP9 | |
| SCHEMBL2361594 | 0.79 | LMNA (0.49) | GAAMMP2MMP3MMP9MMP8 | |
| SCHEMBL5768400 | 0.79 | CTSK (0.43) | MMP2MMP3MMP9MMP8MMP13 | |
| SCHEMBL18613893 | 0.77 | KDM4E (0.49) | ALDH1A1LMNAKDM4E | |
| SCHEMBL8922008 | 0.77 | CHRM4 (0.59) | GAAALDH1A1PRMT5WDR77LMNA | |
| SCHEMBL29429485 | 0.77 | LMNA (0.47) | GAAMMP2MMP3MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294700-A2 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000631-A2 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |