SCHEMBL7206015

SCHEMBL7206015

NCCCCCNCCN

nearest known ligand 0.93

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.81
CA6 P23280 5/20 0.81
CA7 P43166 5/20 0.81
CA9 Q16790 5/20 0.81
CA14 Q9ULX7 5/20 0.81
CA5B Q9Y2D0 5/20 0.81
CA2 P00918 4/20 0.81
CA4 P22748 4/20 0.81
CA5A P35218 4/20 0.81
ALOX15 P16050 3/20 0.81
CA3 P07451 3/20 0.81
F13A1 P00488 2/20 0.81
CYP1A2 P05177 2/20 0.81
THPO P40225 2/20 0.81
CA1 P00915 2/20 0.81
CYP2C9 P11712 1/20 0.81
PKM P14618 1/20 0.81
TSHR P16473 1/20 0.81
MTOR P42345 1/20 0.81
LMNA P02545 3/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL817205 1.00 CA12 (0.81) CA12CA6CA7CA9CA14
SCHEMBL18700922 1.00 CA12 (0.81) CA12CA6CA7CA9CA14
SCHEMBL14030615 1.00 CA12 (0.81) CA12CA6CA7CA9CA14
SCHEMBL15306482 1.00 CA12 (0.81) CA12CA6CA7CA9CA14
SCHEMBL18784646 1.00 CA12 (0.81) CA12CA6CA7CA9CA14
SCHEMBL27516113 1.00 CA12 (0.81) CA12CA6CA7CA9CA14
SCHEMBL18496764 0.97 CA12 (0.88) CA12CA6CA7CA9CA14
Water SCHEMBL29135283 0.97 CA12 (0.77) CA12CA6CA7CA9CA14
Trientine SCHEMBL15016070 0.97 CA12 (0.77) CA12CA6CA7CA9CA14
SCHEMBL16281062 0.97 CA12 (0.87) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207292-A1 BORONIC ACID COMPOUNDS, COMPOSITIONS AND METHODS TRUSTEES OF TUFTS COLLEGE 2024-06-27 US disclosed
US-12016922-B2 Stabilized aqueous antibody compositions ARECOR LIMITED (GB) 2024-06-25 US disclosed
US-12016913-B2 Immunogenic compositions and uses thereof PFIZER INC. (US) 2024-06-25 US disclosed
US-11912114-B2 Electrochromic sunroof based on all solid-state flexible thin film electrochromic device and methods to fabricate the same Shenzhen Guangyi Tech Co., Ltd. (CN) 2024-02-27 US disclosed
US-11912950-B2 Use of nitrogen compounds quaternised with alkylene oxide and hydrocarbyl-substituted polycarboxylic acid as additives in fuels and lubricants BASF SE (DE) 2024-02-27 US disclosed
US-11872537-B2 Metal-organic frameworks for carbon dioxide capture ExxonMobil Technology and Engineering Company (US) 2024-01-16 US disclosed
US-11834607-B2 Additives for enhanced extraction of bitumen DOW GLOBAL TECHNOLOGIES LLC (US) 2023-12-05 US disclosed
US-20230381861-A1 METHOD FOR MANUFACTURING IRON (Fe)-NICKEL (Ni) ALLOY POWDER SUMITOMO METAL MINING CO., LTD. (JP) 2023-11-30 US disclosed
US-11828685-B2 Syntactic foams as mechanically-triggered capture vehicles RESEARCH TRIANGLE INSTITUTE (US) 2023-11-28 US disclosed
US-11820726-B2 Motuporamine derivatives as antimicrobial agents and antibiotic enhancers against resistant gram-negative bacteria UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-11-21 US disclosed
US-20110071059-A1 FOAMERS FOR DOWNHOLE INJECTION CHAMPIONX LLC 2011-03-24 US disclosed
US-20110052673-A1 THERAPEUTIC COMPOSITIONS SHIRE HUMAN GENETIC THERAPIES, INC. 2011-03-03 US disclosed
US-20110009641-A1 Amine-containing lipids and uses thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-01-13 US disclosed
US-20100331234-A1 AMINOALCOHOL LIPIDOIDS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-12-30 US disclosed
US-20100029991-A1 METHOD FOR PRODUCING TRIETHYLENETETRAMINE BASF SE (DE) 2010-02-04 US disclosed
EP-0912584-B1 NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS HOFFMANN LA ROCHE (CH) 2002-12-18 EP disclosed
US-6022892-A Bis-platinum complexes with polyamine ligands as antitumor agents HOFFMAN-LA ROCHE INC. (US) 2000-02-08 US disclosed
EP-0912584-A2 NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS F. HOFFMANN-LA ROCHE AG (CH) 1999-05-06 EP disclosed
WO-1998003519-A9 NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS 1998-07-16 WO disclosed
WO-1998003519-A2 NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS F. HOFFMANN-LA ROCHE AG (CH) 1998-01-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11820726-B2 Motuporamine derivatives as antimicrobial agents and antibiotic enhancers against resistant gram-negative bacteria MGAM, PGLS, NISCH CA12 4851/4885CA6 4102/4885CA7 4347/4885
US-20110052673-A1 THERAPEUTIC COMPOSITIONS PHOSPHO1, SGMS1, APOB CA12 1652/4885CA6 1373/4885CA7 2764/4885
US-20110009641-A1 Amine-containing lipids and uses thereof PHOSPHO1, CHMP4B, SGMS1 CA12 4058/4885CA6 1593/4885CA7 2387/4885
US-20100029991-A1 METHOD FOR PRODUCING TRIETHYLENETETRAMINE TET1, TET3, TET2 CA12 2019/4885CA6 1770/4885CA7 2066/4885
US-11872537-B2 Metal-organic frameworks for carbon dioxide capture MT-CO2, TMCO1, SLC6A12 CA12 13/4885CA6 81/4885CA7 60/4885
US-11912950-B2 Use of nitrogen compounds quaternised with alkylene oxide and hydrocarbyl-substituted polycarboxylic acid as additives in fuels and lubricants DGKI, DERL1, DEK CA12 1074/4885CA6 1114/4885CA7 2072/4885
US-12016913-B2 Immunogenic compositions and uses thereof FCGR3B, SIGLEC7, SIGLEC9 CA12 139/4885CA6 413/4885CA7 213/4885
US-20240207292-A1 BORONIC ACID COMPOUNDS, COMPOSITIONS AND METHODS BCL6B, BCL6, BTD CA12 95/4885CA6 20/4885CA7 38/4885
US-12016922-B2 Stabilized aqueous antibody compositions IGLV6-57, FCGRT, PA2G4 CA12 737/4885CA6 3843/4885CA7 3689/4885
US-20100331234-A1 AMINOALCOHOL LIPIDOIDS AND USES THEREOF PHOSPHO1, PNMT, AASDHPPT CA12 4669/4885CA6 4444/4885CA7 4866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.