Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RNF4 | P78317 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 5/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309991 | 0.99 | LMNA (0.41) | LMNAALDH1A1MAPTRNF4MEN1 | |
| SCHEMBL7311858 | 0.90 | MMP1 (0.45) | LMNAALDH1A1MAPTRNF4MMP1 | |
| SCHEMBL7307984 | 0.87 | ALDH1A1 (0.39) | LMNAALDH1A1MAPTGAARAB9A | |
| SCHEMBL7306362 | 0.84 | MMP1 (0.49) | LMNAALDH1A1MAPTRNF4MEN1 | |
| SCHEMBL7305353 | 0.83 | MMP1 (0.48) | LMNAALDH1A1MAPTRNF4MEN1 | |
| SCHEMBL7303726 | 0.81 | ALDH1A1 (0.44) | LMNAALDH1A1MAPTRNF4MEN1 | |
| SCHEMBL7300368 | 0.81 | MMP1 (0.40) | ALDH1A1MMP1MMP2MMP13HPGD | |
| SCHEMBL7308043 | 0.81 | MMP1 (0.46) | ALDH1A1MMP1MMP2MMP13HPGD | |
| SCHEMBL7306527 | 0.81 | NPC1 (0.36) | MMP1MMP2MMP13LTA4HRAB9A | |
| SCHEMBL7307399 | 0.80 | ALDH1A1 (0.43) | LMNAALDH1A1MAPTRNF4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780386-B1 | Matrix metalloprotease inhibitors | HOFFMANN LA ROCHE (CH) | 2002-10-02 | — | — | EP | disclosed |
| EP-0780386-A1 | Matrix metalloprotease inhibitors | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-25 | — | — | EP | disclosed |