Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.38 |
| ▸ | RNF4 | P78317 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303726 | 0.99 | ALDH1A1 (0.44) | ALDH1A1FFAR1MEN1GLAKMT2A | |
| SCHEMBL7305353 | 0.87 | MMP1 (0.48) | ALDH1A1MEN1GLAKMT2ALMNA | |
| SCHEMBL7298947 | 0.86 | MMP1 (0.47) | ALDH1A1FFAR1KMT2ALMNAEGLN2 | |
| SCHEMBL7306362 | 0.85 | MMP1 (0.49) | ALDH1A1MEN1GLAKMT2ALMNA | |
| SCHEMBL7310236 | 0.83 | HSD11B1 (0.44) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7309991 | 0.82 | LMNA (0.41) | ALDH1A1MEN1GLAKMT2ALMNA | |
| SCHEMBL618046 | 0.82 | FFAR1 (0.41) | ALDH1A1FFAR1KMT2AUSP2HPGD | |
| SCHEMBL7299168 | 0.80 | LMNA (0.39) | ALDH1A1MEN1GLAKMT2ALMNA | |
| SCHEMBL7308120 | 0.78 | OPRK1 (0.47) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL6658727 | 0.77 | ADAM17 (0.47) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780386-B1 | Matrix metalloprotease inhibitors | HOFFMANN LA ROCHE (CH) | 2002-10-02 | — | — | EP | disclosed |
| EP-0780386-A1 | Matrix metalloprotease inhibitors | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-25 | — | — | EP | disclosed |