Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218199 | 0.88 | MMP1 (0.49) | MMP1MMP3MMP9MAPTTDP1 | |
| SCHEMBL7307169 | 0.88 | CCKBR (0.44) | MMP1MMP3MMP9MAPTTDP1 | |
| SCHEMBL7302254 | 0.87 | TDP1 (0.46) | MMP1MMP3MMP9MAPTTDP1 | |
| SCHEMBL9223666 | 0.85 | REN (0.49) | MAPTTDP1RENKLK5 | |
| SCHEMBL8438729 | 0.82 | MEN1 (0.47) | MMP1MMP3MMP9MAPTTDP1 | |
| SCHEMBL9215215 | 0.82 | ITGB3 (0.52) | MMP1MMP3MMP9ITGB3ITGA2B | |
| SCHEMBL9339365 | 0.81 | MAPT (0.45) | ITGB3ITGA2BMAPTTDP1REN | |
| Iodide SCHEMBL9215204 | 0.81 | ITGB3 (0.51) | MMP1MMP3MMP9ITGB3ITGA2B | |
| SCHEMBL9218412 | 0.80 | ST14 (0.47) | MMP1MMP3MMP9ITGB3ITGA2B | |
| Iodide SCHEMBL9218396 | 0.79 | ST14 (0.47) | MMP1MMP3MMP9ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | disclosed |
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | disclosed |