Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 17/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7318294 | 0.77 | NTSR1 (0.45) | ICMT | |
| SCHEMBL29165022 | 0.72 | PLA2G2A (0.54) | ICMTSCN9AIDO1 | |
| Trifluoroacetic Acid SCHEMBL7317627 | 0.72 | EGFR (0.55) | ICMT | |
| SCHEMBL18555893 | 0.71 | ICMT (0.47) | ICMT | |
| Trifluoroacetic Acid SCHEMBL7399152 | 0.71 | SIRT1 (0.45) | ICMT | |
| Hydrochloric Acid SCHEMBL7319385 | 0.70 | HTR6 (0.66) | — | |
| Hydrochloric Acid SCHEMBL7311237 | 0.69 | ALOX5 (0.45) | ICMTSCN9A | |
| SCHEMBL29774760 | 0.66 | ICMT (0.45) | ICMT | |
| SCHEMBL20329709 | 0.66 | ICMT (0.45) | ICMT | |
| SCHEMBL27751729 | 0.66 | ICMT (0.56) | ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | claimed |
| US-20020004198-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2002-01-10 | — | — | US | disclosed |
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | disclosed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | CTSL, MMP8, SERPINB1 | ICMT 1459/4885SCN9A 4828/4885IDO1 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.