Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 16/20 | 0.43 |
| ▸ | MMP9 | P14780 | 15/20 | 0.43 |
| ▸ | MMP1 | P03956 | 11/20 | 0.43 |
| ▸ | MMP2 | P08253 | 9/20 | 0.43 |
| ▸ | MMP8 | P22894 | 9/20 | 0.43 |
| ▸ | MMP12 | P39900 | 6/20 | 0.43 |
| ▸ | MMP14 | P50281 | 6/20 | 0.43 |
| ▸ | MMP16 | P51512 | 6/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 6/20 | 0.43 |
| ▸ | MMP3 | P08254 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324220 | 0.94 | MMP13 (0.46) | MMP13MMP9MMP1MMP2MMP8 | |
| SCHEMBL7324047 | 0.92 | GABRG2 (0.42) | MMP13MMP9MMP1MMP2MMP8 | |
| SCHEMBL7317430 | 0.88 | MMP9 (0.44) | MMP13MMP9MMP1MMP2MMP8 | |
| SCHEMBL7323008 | 0.86 | MMP1 (0.47) | MMP13MMP9MMP1MMP2MMP8 | |
| SCHEMBL7319136 | 0.85 | SMN1; SMN2 (0.40) | MMP13MMP9MMP1MMP2MMP8 | |
| SCHEMBL7321745 | 0.85 | MMP13 (0.49) | MMP13MMP9MMP1MMP2MMP8 | |
| SCHEMBL7319818 | 0.85 | MAPT (0.39) | MMP13MMP9MMP1MMP2MMP8 | |
| SCHEMBL7311368 | 0.84 | METAP2 (0.43) | MMP13MMP9MMP1MMP2MMP8 | |
| SCHEMBL7322262 | 0.84 | LMNA (0.43) | MMP13MMP9MMP1MMP2MMP8 | |
| SCHEMBL7314515 | 0.84 | KDM4E (0.41) | MMP13MMP9MMP1MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |