Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 3/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357801 | 0.82 | MMP8 (0.45) | KDM4AKDM4CKDM5APHF8KDM2A | |
| SCHEMBL7361196 | 0.80 | ALOX5 (0.50) | ALOX5MMP8HPGD | |
| SCHEMBL3842681 | 0.71 | TAAR1 (0.48) | ALOX5 | |
| SCHEMBL7358090 | 0.68 | ERAP2 (0.46) | ALOX5MMP8 | |
| SCHEMBL7348722 | 0.68 | MMP8 (0.40) | KDM4CKDM5APHF8MMP8 | |
| SCHEMBL7357356 | 0.67 | ALOX5 (0.54) | KDM4AKDM4CKDM5APHF8KDM2A | |
| SCHEMBL7349646 | 0.67 | CSNK1E (0.44) | — | |
| SCHEMBL7357535 | 0.67 | CSNK1E (0.44) | — | |
| SCHEMBL7373357 | 0.66 | MMP2 (0.57) | MMP8 | |
| SCHEMBL7356063 | 0.64 | ALOX5 (0.49) | KDM4AKDM4CKDM5APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009736-A1 | MALONIC ACID BASED MATRIX METALLOPROTEINASE INHIBITORS | Roche Diagnostics GmbH (DE) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999011608-A1 | MALONIC ACID BASED MATRIX METALLOPROTEINASE INHIBITORS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-03-11 | — | — | WO | disclosed |