Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 9/20 | 0.37 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7392061 | 0.84 | REN (0.40) | RENBCHE | |
| SCHEMBL7396361 | 0.77 | PSEN1 (0.39) | RENMMP3PSEN1PSEN2APH1B | |
| SCHEMBL7397455 | 0.76 | BCHE (0.36) | RENBCHE | |
| SCHEMBL7327628 | 0.74 | REN (0.51) | RENMMP3PSEN1PSEN2APH1B | |
| SCHEMBL7395179 | 0.71 | MMP2 (0.43) | BCHECYP3A4TSHR | |
| SCHEMBL7327623 | 0.71 | REN (0.63) | REN | |
| SCHEMBL7425908 | 0.66 | MMP3 (0.39) | RENMMP3PSEN1PSEN2APH1B | |
| SCHEMBL7875195 | 0.64 | SIGMAR1 (0.47) | — | |
| SCHEMBL2636331 | 0.60 | TRPA1 (0.50) | BCHETSHR | |
| SCHEMBL29068018 | 0.59 | KMT2A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354767-A | Renin inhibiting polyhydroxy-monoamides | BIO-MEGA, INC. (CA) | 1994-10-11 | — | — | US | claimed |
| US-5354767-A | Renin inhibiting polyhydroxy-monoamides | BIO-MEGA, INC. (CA) | 1994-10-11 | — | — | US | disclosed |