Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.45 |
| ▸ | CPA3 | P15088 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428787 | 0.84 | KMT2A (0.45) | CPA3FOLH1ENPP2LMNAALDH1A1 | |
| SCHEMBL7428456 | 0.81 | PLA2G10 (0.45) | PLA2G10PLA2G5ENPP2CTSSCTSK | |
| SCHEMBL7445692 | 0.81 | ENPP2 (0.36) | CPA3FOLH1ENPP2LMNAALDH1A1 | |
| SCHEMBL7432640 | 0.78 | ENPP2 (0.47) | CPA3FOLH1ENPP2ALDH1A1PKM | |
| SCHEMBL7440464 | 0.78 | FOLH1 (0.41) | CPA3FOLH1ALDH1A1PKM | |
| SCHEMBL7426519 | 0.78 | MME (0.42) | CPA3FOLH1ENPP2ALDH1A1PKM | |
| SCHEMBL7435994 | 0.76 | MME (0.41) | CPA3FOLH1ENPP2ALDH1A1PKM | |
| SCHEMBL7737652 | 0.74 | PLA2G10 (0.50) | PLA2G10PLA2G5ALDH1A1KDM4EOPRM1 | |
| SCHEMBL7446522 | 0.73 | CPA3 (0.44) | CPA3FOLH1ALDH1A1PKM | |
| SCHEMBL7442303 | 0.71 | ALDH1A1 (0.53) | CPA3FOLH1LMNAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |