Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.41 |
| ▸ | ACE | P12821 | 4/20 | 0.41 |
| ▸ | CPA3 | P15088 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426519 | 0.93 | MME (0.42) | MMEACECPA3FOLH1ENPP2 | |
| SCHEMBL7428787 | 0.85 | KMT2A (0.45) | MMEACECPA3FOLH1ENPP2 | |
| SCHEMBL7432640 | 0.81 | ENPP2 (0.47) | CPA3FOLH1ENPP2ALDH1A1PKM | |
| SCHEMBL7436003 | 0.79 | HDAC6 (0.42) | ACEENPP2PTGER4PTGER3PTGER2 | |
| SCHEMBL7445692 | 0.77 | ENPP2 (0.36) | MMECPA3FOLH1ENPP2ALDH1A1 | |
| SCHEMBL7428452 | 0.76 | PLA2G10 (0.45) | CPA3FOLH1ENPP2ALDH1A1PKM | |
| SCHEMBL7442303 | 0.75 | ALDH1A1 (0.53) | CPA3FOLH1ALDH1A1PKMHSD17B10 | |
| SCHEMBL7446522 | 0.74 | CPA3 (0.44) | MMECPA3FOLH1ALDH1A1PKM | |
| SCHEMBL7440464 | 0.74 | FOLH1 (0.41) | MMEACECPA3FOLH1ALDH1A1 | |
| SCHEMBL7440724 | 0.73 | HRH4 (0.43) | ENPP2ALDH1A1MEN1KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |