Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436820 | 0.85 | LMNA (0.45) | MAPTADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL7430118 | 0.82 | TAAR1 (0.40) | KMT2A | |
| SCHEMBL7437379 | 0.81 | MAOA (0.35) | MAPTTHRBKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL7446515 | 0.80 | MTNR1A (0.48) | MAPTKMT2AMEN1SMN1; SMN2ADRA1A | |
| SCHEMBL7440201 | 0.79 | ADRB2 (0.38) | MAPTADRB2ADRB1ADRB3THRA | |
| SCHEMBL7445352 | 0.78 | CA2 (0.40) | MAPTKMT2AKDM4ESMN1; SMN2CA2 | |
| SCHEMBL7434182 | 0.77 | TAS1R3 (0.31) | MAPTSMN1; SMN2 | |
| SCHEMBL7435505 | 0.77 | PNMT (0.36) | MAPTTHRBKMT2AKDM4EMEN1 | |
| SCHEMBL10993141 | 0.76 | KMT2A (0.39) | MAPTTHRATHRBKMT2AMEN1 | |
| SCHEMBL7438907 | 0.76 | CA2 (0.46) | MAPTKMT2AKDM4EMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |