Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440201 | 0.85 | ADRB2 (0.38) | KDM4EITGB3ITGA2BADRB2ADRB1 | |
| SCHEMBL7435716 | 0.84 | PNMT (0.33) | KDM4ETSHRMAPK1ITGB3ITGA2B | |
| SCHEMBL7434523 | 0.84 | GNAI3 (0.31) | ADRB2ADRB1GNAI3GNAO1GNAI1 | |
| SCHEMBL7433144 | 0.83 | ADRB2 (0.35) | ADRB2ADRB1KMT2AMLNRHTR1A | |
| SCHEMBL7436499 | 0.82 | GNAI3 (0.30) | GNAI3GNAO1GNAI1 | |
| SCHEMBL7440923 | 0.82 | THRA (0.37) | KDM4EITGB3ITGA2BADRB2ADRB1 | |
| SCHEMBL7431324 | 0.81 | CA2 (0.38) | KDM4EADRB2ADRB1KMT2AMLNR | |
| SCHEMBL7435524 | 0.81 | CA2 (0.38) | KDM4ETSHRADRB2ADRB1KMT2A | |
| SCHEMBL7446282 | 0.81 | LMNA (0.41) | ADRB2ADRB1KMT2A | |
| SCHEMBL7437011 | 0.81 | SLC6A4 (0.35) | ADRB2ADRB1KMT2AMLNRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |