Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | EEF2K | O00418 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436003 | 0.85 | HDAC6 (0.42) | ACEPOLBHTTMEN1USP2 | |
| SCHEMBL7432645 | 0.82 | ENPP2 (0.47) | POLBCYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL7426522 | 0.82 | MAPT (0.43) | ACHEPOLBTSHRHTTMEN1 | |
| SCHEMBL7445702 | 0.81 | ACHE (0.40) | ACHEPOLBTSHRHTTMEN1 | |
| SCHEMBL7428792 | 0.79 | CYP2D6 (0.45) | ACEPOLBCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7435831 | 0.76 | ACHE (0.40) | ACHEACEPOLBTSHRHTT | |
| SCHEMBL7440735 | 0.74 | L3MBTL1 (0.42) | MEN1KMT2AGAAL3MBTL1ENPP2 | |
| SCHEMBL7428456 | 0.74 | PLA2G10 (0.45) | ACEPOLBKDM4EENPP2HSD17B2 | |
| SCHEMBL7426794 | 0.73 | POLB (0.37) | POLBHTTMEN1USP2MAPT | |
| SCHEMBL7446529 | 0.72 | ACE (0.41) | ACEPOLBTSHRHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |