Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426522 | 0.93 | MAPT (0.43) | HDAC6HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL7428792 | 0.85 | CYP2D6 (0.45) | KMT2AENPP2POLBACE | |
| SCHEMBL7435811 | 0.85 | ACHE (0.41) | SLC6A3MAPTMEN1USP2KMT2A | |
| SCHEMBL7432645 | 0.81 | ENPP2 (0.47) | HDAC6SMN1; SMN2MAPTMEN1USP2 | |
| SCHEMBL7435994 | 0.79 | MME (0.41) | HDAC6HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL7445702 | 0.77 | ACHE (0.40) | HDAC6SLC6A3SMN1; SMN2MAPTMEN1 | |
| SCHEMBL7428456 | 0.76 | PLA2G10 (0.45) | SMN1; SMN2ENPP2KDM4EPOLBACE | |
| SCHEMBL7446529 | 0.74 | ACE (0.41) | SMN1; SMN2MEN1KMT2AHTTPOLB | |
| SCHEMBL7440468 | 0.74 | POLB (0.37) | SMN1; SMN2MAPTMEN1USP2KMT2A | |
| SCHEMBL7440735 | 0.74 | L3MBTL1 (0.42) | HDAC1MEN1KMT2AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |