Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | CLPP | Q16740 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432640 | 0.84 | ENPP2 (0.47) | ENPP2L3MBTL1CMA1MEN1KMT2A | |
| SCHEMBL7440735 | 0.81 | L3MBTL1 (0.42) | ENPP2L3MBTL1HDAC1CMA1CLPP | |
| SCHEMBL7428787 | 0.76 | KMT2A (0.45) | ENPP2MEN1KMT2AALDH1A1 | |
| SCHEMBL7445692 | 0.75 | ENPP2 (0.36) | ENPP2MEN1KMT2AALDH1A1 | |
| SCHEMBL7426519 | 0.74 | MME (0.42) | ENPP2L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL7435994 | 0.73 | MME (0.41) | ENPP2HDAC1MEN1KMT2AALDH1A1 | |
| SCHEMBL7435805 | 0.72 | CPA3 (0.38) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7426791 | 0.70 | CPA3 (0.38) | L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL7428452 | 0.70 | PLA2G10 (0.45) | HRH4ENPP2ALDH1A1 | |
| SCHEMBL7425886 | 0.69 | HSD11B1 (0.44) | CMA1MEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |