Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279547 | 0.84 | PKM (0.46) | CACNA2D1CACNA1BCACNB1CACNA1CPOLB | |
| SCHEMBL11360120 | 0.84 | CACNA2D1 (0.40) | CACNA2D1CACNA1BCACNB1CACNA1CPOLB | |
| SCHEMBL11850354 | 0.84 | PKM (0.46) | CACNA2D1CACNA1BCACNB1CACNA1CPOLB | |
| SCHEMBL7438870 | 0.83 | CHRM2 (0.44) | CACNA2D1CACNA1BCACNB1CHRM2CHRM1 | |
| SCHEMBL7439650 | 0.79 | CHRM2 (0.56) | CACNA2D1CACNA1BCACNB1CACNA1CPOLB | |
| SCHEMBL7434643 | 0.76 | CES2 (0.38) | CHRM2CHRM1ALDH1A1 | |
| SCHEMBL7437442 | 0.74 | TSHR (0.45) | CACNA2D1CACNA1BCACNB1CACNA1CCHRM2 | |
| SCHEMBL28750556 | 0.72 | P4HB (0.52) | POLBALDH1A1TP53MAPTHSD17B10 | |
| SCHEMBL7434817 | 0.72 | LMNA (0.51) | ALDH1A1CYP1A2 | |
| SCHEMBL7426489 | 0.72 | CHRM2 (0.38) | CHRM2CHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |