Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441378 | 0.85 | TEAD1 (0.54) | CES2CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL7445606 | 0.80 | ADRA1D (0.41) | CACNA2D1CACNA1BCACNB1CACNA1COPRM1 | |
| SCHEMBL7434817 | 0.79 | LMNA (0.51) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6246702 | 0.74 | PNMT (0.57) | CES2EPHX1PNMTACP3 | |
| SCHEMBL7434643 | 0.74 | CES2 (0.38) | CES2EPHX1TEAD1CHRM2 | |
| SCHEMBL7426489 | 0.73 | CHRM2 (0.38) | TEAD1CHRM2 | |
| Hydrochloric Acid SCHEMBL14815137 | 0.73 | ALDH1A1 (0.52) | CES2CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL15797668 | 0.72 | TEAD1 (0.55) | CES2CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL7437442 | 0.72 | TSHR (0.45) | CACNA2D1CACNA1BCACNB1CACNA1CTEAD1 | |
| SCHEMBL8234510 | 0.71 | PNMT (0.54) | CES2EPHX1PNMTACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |