Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433114 | 0.89 | TBXA2R (0.30) | — | |
| SCHEMBL7443545 | 0.88 | ALDH1A1 (0.42) | — | |
| SCHEMBL7445682 | 0.84 | ITGB1 (0.31) | ITGB1ITGA4 | |
| SCHEMBL7437102 | 0.83 | CA2 (0.33) | ITGB1ITGA4 | |
| SCHEMBL7445495 | 0.82 | USP2 (0.32) | ITGB1ITGA4 | |
| SCHEMBL7448384 | 0.82 | MMP8 (0.37) | MMEMAPT | |
| SCHEMBL7433244 | 0.82 | F2 (0.34) | ITGB1ITGA4 | |
| SCHEMBL7433865 | 0.81 | ITGB1 (0.31) | ITGB1ITGA4 | |
| SCHEMBL7429926 | 0.79 | CA12 (0.33) | ITGB1ITGA4 | |
| SCHEMBL7442402 | 0.79 | AKR1C3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814622-A | COMPOUND USEFUL AS TRYPSIN LIKE SERINE PROTEASE AS THROMBIN INHIBITORS | ADIR ET COMPAGNIE (FR) | 1998-09-29 | — | — | US | disclosed |