Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | F11 | P03951 | 3/20 | 0.44 |
| ▸ | TRAF6 | Q9Y4K3 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472833 | 0.94 | MAPT (0.48) | MAPTTP53TRAF6MEN1GAA | |
| SCHEMBL7563746 | 0.91 | MAPT (0.49) | MAPTTP53MEN1KMT2AL3MBTL1 | |
| SCHEMBL7468006 | 0.90 | MAPT (0.46) | MAPTTP53MEN1GAAKMT2A | |
| SCHEMBL7461911 | 0.88 | MAPT (0.44) | MAPTTP53MEN1GAAKMT2A | |
| SCHEMBL7468103 | 0.88 | GAA (0.44) | MAPTTP53MEN1GAAKMT2A | |
| SCHEMBL7566236 | 0.87 | LMNA (0.41) | MAPTTP53MEN1GAAKMT2A | |
| SCHEMBL7467191 | 0.85 | L3MBTL1 (0.45) | MAPTTP53TRAF6KDRMEN1 | |
| Iodide SCHEMBL7468583 | 0.85 | MAPT (0.43) | MAPTTP53TRAF6MEN1GAA | |
| SCHEMBL7468517 | 0.84 | HDAC6 (0.52) | MAPTMEN1KMT2ACMA1SMN1; SMN2 | |
| SCHEMBL7460699 | 0.84 | NLRP3 (0.45) | MAPTTP53MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |