Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CDC42 | P60953 | 1/20 | 0.49 |
| ▸ | RAC1 | P63000 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207784 | 0.87 | MMP2 (0.54) | SMN1; SMN2LMNATDP1MMP13MMP1 | |
| SCHEMBL6934674 | 0.86 | MMP1 (0.48) | SMN1; SMN2LMNATDP1HTTL3MBTL1 | |
| SCHEMBL9768697 | 0.75 | AKR1C3 (0.54) | LMNAAKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL7417705 | 0.75 | MMP1 (0.48) | SMN1; SMN2LMNATDP1HTTL3MBTL1 | |
| SCHEMBL7626661 | 0.74 | MMP13 (0.47) | HTTMMP13MMP1MMP9ADAM17 | |
| SCHEMBL7207035 | 0.74 | MMP1 (0.54) | HTTMMP13MMP1MMP9MMP2 | |
| Naproxen SCHEMBL23753934 | 0.73 | AKR1C3 (0.88) | LMNATDP1L3MBTL1AKR1C3AKR1C2 | |
| SCHEMBL15617672 | 0.73 | NPC1 (0.58) | SMN1; SMN2LMNATDP1HTTL3MBTL1 | |
| SCHEMBL6928764 | 0.73 | MMP9 (0.77) | SMN1; SMN2LMNATDP1HTTL3MBTL1 | |
| SCHEMBL6932013 | 0.72 | ALDH1A1 (0.55) | SMN1; SMN2LMNATDP1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020006922-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | AMERICAN CYANAMID COMPANY (US) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006922-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | MMP12, ADAM33, MMP2 | SMN1; SMN2 3424/4885LMNA 3266/4885TDP1 3272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.