Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1640377 | 0.82 | IDO1 (0.55) | IDO1 | |
| SCHEMBL24732807 | 0.79 | IDO1 (0.42) | IDO1PNMTTAAR1 | |
| SCHEMBL29809253 | 0.79 | IDO1 (0.42) | IDO1PNMTTAAR1 | |
| SCHEMBL566305 | 0.78 | IDO1 (0.36) | IDO1SLC6A2SLC6A4 | |
| SCHEMBL3729703 | 0.77 | PNMT (0.54) | IDO1PNMTTAAR1 | |
| SCHEMBL30822631 | 0.77 | IDO1 (0.41) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL1767780 | 0.77 | IDO1 (0.41) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL8225128 | 0.77 | IDO1 (0.41) | IDO1PNMTSLC6A4 | |
| SCHEMBL13077676 | 0.77 | IDO1 (0.41) | IDO1PNMTTAAR1SLC6A4 | |
| SCHEMBL189771 | 0.76 | TP53 (0.48) | IDO1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232199-B | Synthesis method of 1-chloro-2- (4-ethoxybenzyl) -4-iodobenzene | 南京红杉生物科技有限公司 | 2021-11-30 | — | — | CN | claimed |
| CN-109232199-A | The chloro- 2-(4- ethoxy benzyl of 1-) -4- iodobenzene synthetic method | 南京红杉生物科技有限公司 | 2019-01-18 | — | — | CN | claimed |
| US-20250388615-A9 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | ARDELYX, INC. (US) | 2025-12-25 | — | — | US | disclosed |
| US-20250066410-A1 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | ARDELYX, INC. (US) | 2025-02-27 | — | — | US | disclosed |
| US-20250042930-A1 | METHOD FOR PREPARING ARYL CARBON GLYCOSIDE COMPOUND INCLUDING GLIFLOZIN DRUG | SICHUAN UNIVERSITY (CN) | 2025-02-06 | — | — | US | disclosed |
| US-12084472-B2 | Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists | ARDELYX, INC. (US) | 2024-09-10 | — | — | US | disclosed |
| WO-2023213035-A1 | METHOD FOR PREPARING ARYL CARBON GLYCOSIDE COMPOUND INCLUDING GLIFLOZIN DRUG | 四川大学 | 2023-11-09 | — | — | WO | disclosed |
| CN-116730998-A | Process for preparing aryl carbon glycoside compound | 四川大学华西医院 | 2023-09-12 | — | — | CN | disclosed |
| US-20220306672-A1 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | ARDELYX, INC. (US) | 2022-09-29 | — | — | US | disclosed |
| EP-3390382-B1 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | ARDELYX INC (US) | 2021-12-01 | — | — | EP | disclosed |
| CN-109232199-B | Synthesis method of 1-chloro-2- (4-ethoxybenzyl) -4-iodobenzene | 南京红杉生物科技有限公司 | 2021-11-30 | — | — | CN | disclosed |
| US-20100120714-A1 | SUBSTITUTED BENZENE FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-05-13 | — | — | US | disclosed |
| CN-101686688-A | substituted benzene fungicides | DU PONT | 2010-03-31 | — | — | CN | disclosed |
| EP-2129225-A2 | SUBSTITUTED BENZENE FUNGICIDES | E. I. Du Pont de Nemours and Company (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008124092-A2 | SUBSTITUTED BENZENE FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-16 | — | — | WO | disclosed |
| US-20080200454-A1 | CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. | 2008-08-21 | — | — | US | disclosed |
| WO-2008100618-A2 | CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | WO | disclosed |
| US-20070232626-A1 | Purine Derivatives as A3 and A1 Adenosine Receptor Agonists | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPT OF HEALTH AND H (MD) | 2007-10-04 | — | — | US | disclosed |
| EP-1794162-A1 | PURINE DERIVATIVES AS A3 AND A1 ADENOSINE RECEPTOR AGONISTS | The Government of the United States of America, as repres. by the Secretary of Health and Human Services, Nat. Inst. of Health (US) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006031505-A1 | PURINE DERIVATIVES AS A3 AND A1 ADENOSINE RECEPTOR AGONISTS | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2006-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066410-A1 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | GPR119, GIPR, GLP1R | IDO1 1111/4885PNMT 1139/4885TAAR1 169/4885 |
| US-20250388615-A9 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | GPR119, GIPR, FFAR3 | IDO1 1416/4885PNMT 2080/4885TAAR1 86/4885 |
| US-20250042930-A1 | METHOD FOR PREPARING ARYL CARBON GLYCOSIDE COMPOUND INCLUDING GLIFLOZIN DRUG | UGGT1, GCG, SLC5A2 | IDO1 1708/4885PNMT 4628/4885TAAR1 4719/4885 |
| US-20080200454-A1 | CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | CTSS, CTSK, CTSZ | IDO1 2941/4885PNMT 3898/4885TAAR1 3251/4885 |
| US-20220306672-A1 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | GPR119, GIPR, GLP1R | IDO1 1111/4885PNMT 1139/4885TAAR1 169/4885 |
| US-12084472-B2 | Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists | GPR119, GIPR, GLP1R | IDO1 1111/4885PNMT 1139/4885TAAR1 169/4885 |
| US-20070232626-A1 | Purine Derivatives as A3 and A1 Adenosine Receptor Agonists | ADORA1, ADORA3, ADORA2A | IDO1 3225/4885PNMT 2219/4885TAAR1 130/4885 |
| US-20100120714-A1 | SUBSTITUTED BENZENE FUNGICIDES | NR0B1, CBR3, NR0B2 | IDO1 1241/4885PNMT 3469/4885TAAR1 1781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.