Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7550693 | 0.79 | LMNA (0.36) | MEN1KMT2ABRD4 | |
| Hydrochloric Acid SCHEMBL7556779 | 0.79 | LMNA (0.35) | MEN1KMT2ABRD4 | |
| SCHEMBL7549924 | 0.77 | NPC1 (0.32) | — | |
| SCHEMBL7506577 | 0.74 | PNMT (0.44) | — | |
| SCHEMBL7511439 | 0.72 | PNMT (0.37) | — | |
| SCHEMBL7554137 | 0.71 | KDM4E (0.31) | — | |
| SCHEMBL6555243 | 0.70 | TAS2R38 (0.38) | MEN1KMT2A | |
| SCHEMBL8309546 | 0.70 | FYN (0.47) | — | |
| SCHEMBL7516507 | 0.70 | PNMT (0.42) | — | |
| SCHEMBL8306747 | 0.68 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861250-B1 | AMIDINE AND ISOTHIOUREA DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2002-02-13 | — | — | EP | claimed |