Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29882904 | 0.96 | VCAM1 (0.48) | VCAM1MAPK1POLBTSHRRAD51 | |
| SCHEMBL249876 | 0.96 | VCAM1 (0.48) | VCAM1MAPK1POLBTSHRRAD51 | |
| Potassium Ion SCHEMBL5605743 | 0.81 | ACLY (0.36) | VCAM1RAD51PKMPTGS1 | |
| SCHEMBL30475007 | 0.79 | VCAM1 (0.48) | VCAM1MAPK1POLBTSHRALDH1A1 | |
| SCHEMBL6007987 | 0.79 | VCAM1 (0.48) | VCAM1MAPK1POLBTSHRALDH1A1 | |
| SCHEMBL14401895 | 0.79 | VCAM1 (0.48) | VCAM1MAPK1POLBTSHRALDH1A1 | |
| SCHEMBL249875 | 0.79 | VCAM1 (0.48) | VCAM1MAPK1POLBTSHRALDH1A1 | |
| SCHEMBL7623197 | 0.79 | VCAM1 (0.48) | VCAM1MAPK1POLBTSHRALDH1A1 | |
| SCHEMBL25203443 | 0.78 | VCAM1 (0.47) | VCAM1MAPK1POLBTSHRALDH1A1 | |
| SCHEMBL28707093 | 0.78 | VCAM1 (0.47) | VCAM1MAPK1POLBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140154610-A1 | AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND USES THEREOF | JSR CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| EP-2738194-A1 | AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND APPLICATION THEREOF | JSR Corporation (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8445141-B2 | Sulfonic acid group-containing polymer, method for producing the same, resin composition containing such sulfonic acid group-containing polymer, polymer electrolyte membrane, polymer electrolyte membrane/electrode assembly, and fuel cell | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2013-05-21 | — | — | US | disclosed |
| US-8211576-B2 | aromatic polyether with sulfonic acid-functional block and acid-free blocks; polyether sulfones; polymer electrolyte fuel cells | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-03 | — | — | US | disclosed |
| US-8211558-B2 | Crosslinked polymer electrolyte and method for producing same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-03 | — | — | US | disclosed |
| US-8178590-B2 | Block copolymer and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-15 | — | — | US | disclosed |
| EP-2088167-B1 | Block copolymers and use thereof | SUMITOMO CHEMICAL CO (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7977393-B2 | Composition containing oxocarbon and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7972734-B2 | Process for producing polymer electrolyte emulsion | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-07-05 | — | — | US | disclosed |
| EP-1862489-B1 | Block Copolymer and Use Thereof | SUMITOMO CHEMICAL CO (JP) | 2010-10-06 | — | — | EP | disclosed |
| EP-1845135-A1 | COMPOSITION CONTAINING OXOCARBON AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2007-10-17 | — | — | EP | disclosed |
| US-20070166591-A1 | POLYMER ELECTROLYTE COMPOSITION AND APPLICATION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-07-19 | — | — | US | disclosed |
| US-20070148518-A1 | Polymer electrolyte and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-06-28 | — | — | US | disclosed |
| US-20070083010-A1 | aromatic polyether with sulfonic acid-functional block and acid-free blocks; polyether sulfones; polymer electrolyte fuel cells | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-04-12 | — | — | US | disclosed |
| US-20070066759-A1 | Block copolymers and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-22 | — | — | US | disclosed |
| EP-1698652-A1 | POLYMER ELECTROLYTE AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-1674498-A1 | BLOCK COPOLYMER AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2006-06-28 | — | — | EP | disclosed |
| EP-1669391-A1 | BLOCK COPOLYMERS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-1519435-A1 | POLYMERIC LAMINATES, PROCESSES FOR PRODUCING THE SAME, AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2005-03-30 | — | — | EP | disclosed |
| US-20040186262-A1 | Ion conductive membrane made from a block copolymer and methods of making a block copolymer | GM Global Technology Operations LLC | 2004-09-23 | — | — | US | disclosed |