Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.34 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.34 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.34 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.34 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | DUSP5 | Q16690 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29882904 | 1.00 | VCAM1 (0.48) | VCAM1MAPK1POLBTSHRALDH1A1 | |
| Potassium Ion SCHEMBL756813 | 0.96 | VCAM1 (0.48) | VCAM1MAPK1POLBTSHRALDH1A1 | |
| SCHEMBL3935273 | 0.81 | PKM (0.50) | POLBPKMTDP1PTGS1CA6 | |
| SCHEMBL249875 | 0.79 | VCAM1 (0.48) | VCAM1MAPK1POLBTSHRALDH1A1 | |
| SCHEMBL6007987 | 0.79 | VCAM1 (0.48) | VCAM1MAPK1POLBTSHRALDH1A1 | |
| SCHEMBL7623197 | 0.79 | VCAM1 (0.48) | VCAM1MAPK1POLBTSHRALDH1A1 | |
| SCHEMBL14401895 | 0.79 | VCAM1 (0.48) | VCAM1MAPK1POLBTSHRALDH1A1 | |
| SCHEMBL30475007 | 0.79 | VCAM1 (0.48) | VCAM1MAPK1POLBTSHRALDH1A1 | |
| SCHEMBL25203443 | 0.78 | VCAM1 (0.47) | VCAM1MAPK1POLBTSHRALDH1A1 | |
| SCHEMBL28707093 | 0.78 | VCAM1 (0.47) | VCAM1MAPK1POLBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2816069-B1 | SULFONATED POLYETHERSULFONE COPOLYMER CONTAINING HYDROXYL GROUPS AND PREPARATION METHOD THEREOF, POLYMER ELECTROLYTE MEMBRANE FOR FUEL CELLS AND MEMBRANE ELECTRODE ASSEMBLY COMPRISING THE SAME | KOREA INST SCI & TECH (KR) | 2017-03-29 | — | — | EP | claimed |
| EP-2816069-A1 | Sulfonated polyethersulfone copolymer containing hydroxyl groups and preparation method thereof, polymer electrolyte membrane for fuel cells and membrane electrode assembly comprising the same | Korea Institute of Science and Technology (KR) | 2014-12-24 | — | — | EP | claimed |
| US-20140329169-A1 | SULFONATED POLYETHERSULFONE COPOLYMER CONTAINING HYDROXYL GROUPS AND PREPARATION METHOD THEREOF, POLYMER ELECTROLYTE MEMBRANE FOR FUEL CELLS AND MEMBRANE ELECTRODE ASSEMBLY COMPRISING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-11-06 | — | — | US | claimed |
| US-9722270-B2 | Polymer, electrolyte membrane and electrode for a fuel cell, each including the polymer, fuel cell including at least one of the electrolyte membrane, and the electrode | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-08-01 | — | — | US | disclosed |
| EP-2816069-B1 | SULFONATED POLYETHERSULFONE COPOLYMER CONTAINING HYDROXYL GROUPS AND PREPARATION METHOD THEREOF, POLYMER ELECTROLYTE MEMBRANE FOR FUEL CELLS AND MEMBRANE ELECTRODE ASSEMBLY COMPRISING THE SAME | KOREA INST SCI & TECH (KR) | 2017-03-29 | — | — | EP | disclosed |
| US-9005843-B2 | Polymer electrolyte composition | UBE INDUSTRIES, LTD. (JP) | 2015-04-14 | — | — | US | disclosed |
| US-20150037708-A1 | POLYMER, ELECTROLYTE MEMBRANE AND ELECTRODE FOR A FUEL CELL, EACH INCLUDING THE POLYMER, FUEL CELL INCLUDING AT LEAST ONE OF THE ELECTROLYTE MEMBRANE, AND THE ELECTRODE | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2015-02-05 | — | — | US | disclosed |
| EP-2816069-A1 | Sulfonated polyethersulfone copolymer containing hydroxyl groups and preparation method thereof, polymer electrolyte membrane for fuel cells and membrane electrode assembly comprising the same | Korea Institute of Science and Technology (KR) | 2014-12-24 | — | — | EP | disclosed |
| US-20140329169-A1 | SULFONATED POLYETHERSULFONE COPOLYMER CONTAINING HYDROXYL GROUPS AND PREPARATION METHOD THEREOF, POLYMER ELECTROLYTE MEMBRANE FOR FUEL CELLS AND MEMBRANE ELECTRODE ASSEMBLY COMPRISING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-11-06 | — | — | US | disclosed |
| US-8771897-B2 | Electrolyte membrane for fuel cell including blend of polymers with different degrees of sulfonation, and membrane-electrode assembly and fuel cell including the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-07-08 | — | — | US | disclosed |
| US-8710176-B2 | Method for producing a sulfonated polyarylether block copolymer | UBE INDUSTRIES, LTD. (JP) | 2014-04-29 | — | — | US | disclosed |
| US-7638220-B2 | Polymeric laminates, processes for producing the same, and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20090075147-A1 | Sulfonic acid group-containing polymer, method for producing the same, resin composition containing such sulfonic acid group-containing polymer, polymer electrolyte membrane, polymer electrolyte membrane/electrode assembly, and fuel cell | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2009-03-19 | — | — | US | disclosed |
| US-20080171252-A1 | Novel Polymer Electrolyte, Polymer Electrolyte Composition, Electrolyte Membrane, and Production Method and Use Thereof | UBE INDUSTRIES, LTD. (JP) | 2008-07-17 | — | — | US | disclosed |
| EP-1889863-A1 | SULFONIC ACID GROUP-CONTAINING POLYMER, METHOD FOR PRODUCING SAME, RESIN COMPOSITION CONTAINING SUCH SULFONIC ACID GROUP-CONTAINING POLYMER, POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE/ELECTRODE ASSEMBLY, AND FUEL CELL | Toyo Boseki Kabushiki Kasisha (JP) | 2008-02-20 | — | — | EP | disclosed |
| EP-1855339-A1 | NOVEL POLYMER ELECTROLYTE, POLYMER ELECTROLYTE COMPOSITION, ELECTROLYTE MEMBRANE, AND PRODUCTION METHOD AND USE THEREOF | Ube Industries, Ltd. (JP) | 2007-11-14 | — | — | EP | disclosed |
| US-20060166047-A1 | Polymeric laminates, processes for producing the same, and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1519435-A1 | POLYMERIC LAMINATES, PROCESSES FOR PRODUCING THE SAME, AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2005-03-30 | — | — | EP | disclosed |
| US-6451921-B2 | Block copolymers with sulfonated polyether sulfone units | MEMBRANA GMBH (DE) | 2002-09-17 | — | — | US | disclosed |
| US-20010021764-A1 | Block copolymers with sulfonated polyether sulfone units | MEMBRANA GMBH (DE) | 2001-09-13 | — | — | US | disclosed |