Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 5/20 | 0.35 |
| ▸ | PTGS2 known ✓ | P35354 | 9/20 | 0.35 |
| ▸ | ACLY | P53396 | 4/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL16341241 | 0.92 | PTGS2 (0.42) | ACLYKIF11PTGS1PTGS2PKM | |
| SCHEMBL5277258 | 0.88 | PTGS2 (0.42) | ACLYKIF11PTGS1PTGS2PKM | |
| Potassium Ion SCHEMBL756813 | 0.81 | VCAM1 (0.48) | RAD51PTGS1PKMVCAM1 | |
| SCHEMBL3935273 | 0.78 | PKM (0.50) | PTGS1PTGS2PKM | |
| SCHEMBL29882904 | 0.77 | VCAM1 (0.48) | RAD51PTGS1PKMVCAM1 | |
| SCHEMBL249876 | 0.77 | VCAM1 (0.48) | RAD51PTGS1PKMVCAM1 | |
| Potassium Ion SCHEMBL2176793 | 0.76 | PTK2B (0.43) | ACLYPTGS1PTGS2 | |
| SCHEMBL4553485 | 0.76 | TET2 (0.41) | ACLY | |
| SCHEMBL5605746 | 0.74 | TET2 (0.40) | ACLYPKM | |
| SCHEMBL8379140 | 0.73 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070166591-A1 | POLYMER ELECTROLYTE COMPOSITION AND APPLICATION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-07-19 | — | — | US | disclosed |