SCHEMBL7578265

SCHEMBL7578265

CCCc1cc(-c2ccccc2)ccc1OC(=O)OCC

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.48
PPARG P37231 3/20 0.42
PPARA Q07869 2/20 0.42
PPARD Q03181 1/20 0.42
ESR1 P03372 1/20 0.41
TYMS P04818 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
TARBP2 Q15633 1/20 0.40
DHODH Q02127 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7095256 0.85 CFD (0.50) ALOX5PPARGPPARAPPARD
SCHEMBL7571401 0.83 PPARG (0.52) ALOX5PPARGPPARAPPARDTYMS
SCHEMBL1834659 0.81 THRA (0.48) ALOX5PPARDTYMS
SCHEMBL7571353 0.81 CYP1A2 (0.46) ALOX5PPARGPPARATARBP2DHODH
SCHEMBL7090979 0.75 MGLL (0.40) ALOX5PPARGPPARA
SCHEMBL6223125 0.75 ALDH1A1 (0.41) ALOX5PPARATARBP2
SCHEMBL6976915 0.75 NPC1 (0.51) ALOX5TARBP2
SCHEMBL27427403 0.74 PPARG (0.43) ALOX5PPARGPPARAPPARDGABRA1
SCHEMBL455218 0.74 DCLRE1A (0.42) PPARGPPARAPPARD
SCHEMBL29068251 0.74 SMN1; SMN2 (0.42) ALOX5PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020086892-A1 For controlling animal pests, in particular: insects, arachnids and nematodes BAYER AKTIENGESELLSCHAFT (DE) 2002-07-04 US disclosed
US-6410581-B1 INSECTICIDES, MITICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020086892-A1 For controlling animal pests, in particular: insects, arachnids and nematodes ATXN2, HAX1, ANTXR2 ALOX5 640/4885PPARG 4297/4885PPARA 4505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.