Fluorescein Sodium

Fluorescein Sodium

SCHEMBL264060

O=C([O-])c1ccccc1-c1c2ccc(=O)cc-2oc2cc([O-])ccc12.[Na+].[Na+]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Fluorescein Sodium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 known ✓ P00915 6/20 0.41
CA2 known ✓ P00918 6/20 0.41
THRB known ✓ P10828 2/20 0.41
CA12 known ✓ O43570 2/20 0.38
USP2 O75604 4/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
POLB P06746 3/20 0.50
ATM Q13315 2/20 0.50
PLEC Q15149 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
ABCB1 P08183 1/20 0.44
ALPL P05186 1/20 0.43
ALPI P09923 1/20 0.43
ALPG P10696 1/20 0.43
CFTR P13569 1/20 0.42
PAX8 Q06710 1/20 0.42
GOPC Q9HD26 1/20 0.42
KDM6B O15054 1/20 0.41
KDM4A O75164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorescein Sodium SCHEMBL29364968 1.00 USP2 (0.50) USP2MEN1KMT2APOLBATM
Fluorescein Sodium SCHEMBL29355465 1.00 USP2 (0.50) USP2MEN1KMT2APOLBATM
Potassium Ion SCHEMBL29538524 0.98 USP2 (0.50) USP2MEN1KMT2APOLBATM
SCHEMBL7591289 0.89 USP2 (0.65) USP2MEN1KMT2APOLBATM
SCHEMBL29594855 0.89 USP2 (0.65) USP2MEN1KMT2APOLBATM
SCHEMBL29591827 0.77 USP2 (0.76) USP2MEN1KMT2APOLBATM
SCHEMBL107875 0.77 USP2 (0.76) USP2MEN1KMT2APOLBATM
SCHEMBL29781098 0.77 USP2 (0.76) USP2MEN1KMT2APOLBATM
SCHEMBL10082261 0.76 USP2 (0.56) USP2MEN1KMT2APOLBATM
SCHEMBL8451224 0.76 USP2 (0.74) USP2MEN1KMT2APOLBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240377326-A1 USE OF FLUORESCENT OR VISIBLE TRACERS TO MONITOR NUTRIENT CONCENTRATIONS IN SOLUTION FEHR SOLUTIONS, LLC 2024-11-14 US claimed
WO-2023043974-A1 USE OF FLUORESCENT TRACERS TO MONITOR NUTRIENT CONCENTRATIONS IN SOLUTION FEHR SOLUTIONS, LLC (US) 2023-03-23 WO claimed
CN-102269702-A Detection kit for determining small berry ORAC (oxygen radical absorbance capacity) and detection method thereof 2011-12-07 CN claimed
CN-101120046-B Molded article exhibiting multi-color effects, associated lighting device and resin ARKEMA FRANCE 2011-02-23 CN claimed
US-20030108488-A1 Compositions and methods to inhibit tartar and microbes using denture adhesive compositions with colorants PROCTER & GAMBLE COMPANY, THE 2003-06-12 US claimed
US-20260068887-A1 XANTHENE DYE COMBINATIONS FOR ENHANCED BACTERIAL, YEAST, AND FUNGAL MICROBIAL CONTROL ICHOR MICROBIAL SOLUTIONS INC (US) 2026-03-12 US disclosed
US-20250377301-A1 STABILISED FLUOROPHORES, COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE FREISTAAT BAYERN LUDWIG MAXIMILIANS UNIV MUENCHEN (DE) 2025-12-11 US disclosed
EP-4638693-A1 AEROSOL DEPOSITION DEVICE LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST) (LU) 2025-10-29 EP disclosed
US-12303582-B2 Composition for the treatment of nail fungus OYSTERSHELL NV (BE) 2025-05-20 US disclosed
EP-4305183-B1 METHODS FOR DELIVERING A CARGO INTO A CELL Trince bv (BE) 2025-05-07 EP disclosed
US-20250108658-A1 INKJET PRINTING PROCESSES FOR TEMPORARY TATTOOS Prism Inks, Inc. (US) 2025-04-03 US disclosed
EP-4069643-B1 METHODS AND SYSTEMS FOR MONITORING OR CONTROLLING ANTI-SCALANT CONCENTRATION STERLING SPECIALTY CHEMICALS HOLDING UK LTD (GB) 2025-03-19 EP disclosed
US-20030183575-A1 METHOD OF MONITORING MEMBRANE SEPARATION PROCESSES ECOLAB USA INC. 2003-10-02 US disclosed
US-20030108488-A1 Compositions and methods to inhibit tartar and microbes using denture adhesive compositions with colorants PROCTER & GAMBLE COMPANY, THE 2003-06-12 US disclosed
US-20030071212-A1 Method of tracing drains ECOLAB USA INC. 2003-04-17 US disclosed
WO-2003029794-A1 METHOD OF TRACING DRAINS ONDEO NALCO COMPANY (US) 2003-04-10 WO disclosed
US-6391281-B1 TOPICALLY APPLYING FLUORESCING AGENT TO CUT TOOTH OR RESTORATION SURFACE, IRRADIATING WITH LIGHT SOURCE EMITTING WAVELENGTH IN VISIBLE SPECTRUM, OBSERVING EMITTED FLUORESCENCE TO DISTINGUISH DENTIN FROM ENAMEL OR RESTORATION MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE 2002-05-21 US disclosed
WO-2001087240-A1 FLUORESCENT AGENT FOR THE IDENTIFICATION OF TOOTH DENTIN MCG RESEARCH INSTITUTE (US) 2001-11-22 WO disclosed
US-5932031-A Fluorescent water soluble solder flux INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1999-08-03 US disclosed
US-5820697-A Fluorescent water soluble solder flux INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1998-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260068887-A1 XANTHENE DYE COMBINATIONS FOR ENHANCED BACTERIAL, YEAST, AND FUNGAL MICROBIAL CONTROL TYR, PPOX, TH CA1 3446/4885CA2 935/4885THRB 2676/4885
US-20250377301-A1 STABILISED FLUOROPHORES, COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE CRY1, MKI67, IK CA1 712/4885CA2 425/4885THRB 4122/4885
US-12303582-B2 Composition for the treatment of nail fungus DPM1, PIK3C3, ETF1 CA1 1300/4885CA2 595/4885THRB 3176/4885
US-20030108488-A1 Compositions and methods to inhibit tartar and microbes using denture adhesive compositions with colorants TAS2R10, TAS1R1, TAS2R40 CA1 1348/4885CA2 2014/4885THRB 1948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.