Fluorescein Sodium

Fluorescein Sodium

SCHEMBL29355465

O=C([O-])c1ccccc1-c1c2ccc(=O)cc-2oc2cc([O-])ccc12.[Na+].[Na+]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Fluorescein Sodium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 known ✓ P00915 6/20 0.41
CA2 known ✓ P00918 6/20 0.41
THRB known ✓ P10828 2/20 0.41
CA12 known ✓ O43570 2/20 0.38
USP2 O75604 4/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
POLB P06746 3/20 0.50
ATM Q13315 2/20 0.50
PLEC Q15149 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
ABCB1 P08183 1/20 0.44
ALPL P05186 1/20 0.43
ALPI P09923 1/20 0.43
ALPG P10696 1/20 0.43
CFTR P13569 1/20 0.42
PAX8 Q06710 1/20 0.42
GOPC Q9HD26 1/20 0.42
KDM6B O15054 1/20 0.41
KDM4A O75164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorescein Sodium SCHEMBL29364968 1.00 USP2 (0.50) USP2MEN1KMT2APOLBATM
Fluorescein Sodium SCHEMBL264060 1.00 USP2 (0.50) USP2MEN1KMT2APOLBATM
Potassium Ion SCHEMBL29538524 0.98 USP2 (0.50) USP2MEN1KMT2APOLBATM
SCHEMBL7591289 0.89 USP2 (0.65) USP2MEN1KMT2APOLBATM
SCHEMBL29594855 0.89 USP2 (0.65) USP2MEN1KMT2APOLBATM
SCHEMBL29591827 0.77 USP2 (0.76) USP2MEN1KMT2APOLBATM
SCHEMBL107875 0.77 USP2 (0.76) USP2MEN1KMT2APOLBATM
SCHEMBL29781098 0.77 USP2 (0.76) USP2MEN1KMT2APOLBATM
SCHEMBL10082261 0.76 USP2 (0.56) USP2MEN1KMT2APOLBATM
SCHEMBL8451224 0.76 USP2 (0.74) USP2MEN1KMT2APOLBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
WO-2025090061-A1 ULTRASONIC INDICATOR DEVICE AND METHOD FOR MONITORING ULTRASONICATION JP LABORATORIES, INC. (US) 2025-05-01 WO claimed
WO-2025075611-A1 ULTRASONIC INDICATOR BASED ON EMULSION FORMATION JP LABORATORIES, INC. (US) 2025-04-10 WO claimed
CN-117630356-A Method and reagent for detecting bacterial vesicle 南方医科大学南方医院 2024-03-01 CN claimed
US-11643560-B2 Ink, ink stored container, inkjet printing method, and inkjet printing apparatus RICOH COMPANY, LTD. (JP) 2023-05-09 US claimed
CN-115808395-A Method for screening grafting compatibility stock by using spectrum and fluorescent probe 华中农业大学 2023-03-17 CN claimed
CN-112322715-B Nucleic acid sequencing method 清华大学 2022-11-25 CN claimed
WO-2022105640-A1 NUCLEIC ACID SEQUENCING METHOD 清华大学 2022-05-27 WO claimed
CN-109575689-B Ink for ink jet printing, ink set for ink jet printing, and printing method 精工爱普生株式会社 2022-03-25 CN claimed
US-20260137591-A1 COMPOSITIONS AND DEVICES FOR CONTAINING MEDICAL FLUIDS ICU MEDICAL INC (US) 2026-05-21 US disclosed
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN disclosed
US-12629001-B2 Method, apparatus and system for providing medical diagnosis assistance information based on artificial intelligence VPIX Medical Incorporation (KR) 2026-05-19 US disclosed
US-20260124324-A1 PHOTOCLICK CHEMISTRY OF SILK FOR TEMPORARY UV TATTOOS TUFTS COLLEGE (US) 2026-05-07 US disclosed
EP-4735018-A2 CENTRIFUGALLY-MOLDED ARTICLES AND METHODS Trustees Of Tufts College (US) 2026-05-06 EP disclosed
CN-109575689-B Ink for ink jet printing, ink set for ink jet printing, and printing method 精工爱普生株式会社 2022-03-25 CN disclosed
EP-3965724-A1 FORMULATIONS AND METHODS FOR PREPARING STABLE COSMETIC COMPOSITIONS Spinart, LLC (US) 2022-03-16 EP disclosed
US-11273223-B2 Bispecific anti-hapten/anti-blood brain barrier receptor antibodies, complexes thereof and their use as blood brain barrier shuttles HOFFMANN-LA ROCHE INC. (US) 2022-03-15 US disclosed
EP-3960768-A1 BISPECIFIC ANTI-HAPTEN/ANTI-BLOOD BRAIN BARRIER RECEPTOR ANTIBODIES, COMPLEXES THEREOF AND THEIR USE AS BLOOD BRAIN BARRIER SHUTTLES F. Hoffmann-La Roche AG (CH) 2022-03-02 EP disclosed
US-20220051400-A1 SYSTEMS, METHODS, AND MEDIA FOR AUTOMATICALLY TRANSFORMING A DIGITAL IMAGE INTO A SIMULATED PATHOLOGY IMAGE DIGNITY HEALTH 2022-02-17 US disclosed
US-11229584-B2 Pigment dispersion liquid for cosmetics, and aqueous liquid cosmetic using same MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2022-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137591-A1 COMPOSITIONS AND DEVICES FOR CONTAINING MEDICAL FLUIDS TFEB, LAGE3, RICTOR CA1 3723/4885CA2 3780/4885THRB 4180/4885
US-20260124324-A1 PHOTOCLICK CHEMISTRY OF SILK FOR TEMPORARY UV TATTOOS PTMS, ITK, MATK CA1 4842/4885CA2 4601/4885THRB 2085/4885
US-12629001-B2 Method, apparatus and system for providing medical diagnosis assistance information based on artificial intelligence TFEB, DNER, CNN2 CA1 4547/4885CA2 2424/4885THRB 3339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.