Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9290880 | 0.81 | SSTR4 (0.45) | TSHRCA2DYRK1AIGF1RHPGD | |
| SCHEMBL7336911 | 0.80 | CA2 (0.43) | TSHRCA2DYRK1AIGF1RHPGD | |
| SCHEMBL4197198 | 0.80 | CA2 (0.43) | TSHRCA2DYRK1AIGF1RHPGD | |
| SCHEMBL5695473 | 0.79 | CA2 (0.46) | TSHRCA2HPGD | |
| SCHEMBL6493103 | 0.79 | GABRA1 (0.47) | TSHRCA2HPGD | |
| SCHEMBL9379705 | 0.79 | CA2 (0.43) | TSHRALDH1A1HSD17B10TDP1CA2 | |
| SCHEMBL12038566 | 0.75 | CA2 (0.40) | TSHRALDH1A1HSD17B10TDP1CA2 | |
| Salicylic Acid SCHEMBL7597669 | 0.74 | ALDH1A1 (0.50) | TSHRALDH1A1HSD17B10TDP1KDM4E | |
| SCHEMBL12038576 | 0.74 | CA2 (0.39) | TSHRPIN1CA2HPGD | |
| SCHEMBL7867727 | 0.73 | CYP4F2 (0.45) | TSHRALDH1A1HSD17B10TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498191-B2 | FOR TREATMENT OF ALZHEIMER'S DISEASE, DIABETES MELLITUS, PARKINSON'S DISEASE, NEURONAL AND CARDIAC ISCHEMIA, HUNTINGTON'S DISEASE, STROKE | MITOKOR | 2002-12-24 | — | — | US | disclosed |
| US-20020010195-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | GHOSH SOUMITRA S (US) | 2002-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010195-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | TFAM, HSPA9, HSPD1 | TSHR 4712/4885ALDH1A1 945/4885HSD17B10 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.