Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.39 |
| ▸ | TLR4 known ✓ | O00206 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154820 | 1.00 | RECQL (0.70) | RECQLTSHRCYP3A4ATMTDP1 | |
| SCHEMBL4070013 | 0.99 | RECQL (0.71) | RECQLTSHRCYP3A4ATMTDP1 | |
| Docusate SCHEMBL6239044 | 0.97 | RECQL (0.74) | RECQLTSHRCYP3A4ATMTDP1 | |
| Docusate SCHEMBL14482029 | 0.96 | RECQL (0.76) | RECQLTSHRCYP3A4ATMTDP1 | |
| Docusate SCHEMBL3041223 | 0.95 | RECQL (0.78) | RECQLTSHRCYP3A4ATMTDP1 | |
| Docusate SCHEMBL9722552 | 0.95 | RECQL (0.78) | RECQLTSHRCYP3A4ATMTDP1 | |
| Docusate SCHEMBL4113 | 0.95 | RECQL (0.78) | RECQLTSHRCYP3A4ATMTDP1 | |
| Docusate SCHEMBL11580011 | 0.94 | RECQL (0.76) | RECQLTSHRCYP3A4ATMTDP1 | |
| Docusate SCHEMBL465322 | 0.94 | RECQL (0.76) | RECQLTSHRCYP3A4ATMTDP1 | |
| Docusate SCHEMBL22588804 | 0.94 | RECQL (0.76) | RECQLTSHRCYP3A4ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020058051-A1 | SKIN CARE COMPOSITIONS | NAWAZ ZAHID (GB) | 2002-05-16 | — | — | US | disclosed |
| EP-0906077-A4 | SKIN CARE COMPOSITIONS | PROCTER & GAMBLE (US) | 2001-12-12 | — | — | EP | disclosed |
| EP-0884996-A4 | SKIN CARE COMPOSITIONS | PROCTER & GAMBLE (US) | 2001-05-30 | — | — | EP | disclosed |
| EP-1051149-A1 | COSMETIC COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-15 | — | — | EP | disclosed |
| EP-0778765-A4 | COSMETIC MAKE-UP COMPOSITIONS | PROCTER & GAMBLE (US) | 2000-04-19 | — | — | EP | disclosed |
| US-6013269-A | OIL-IN-WATER EMULSION COMPRISING VOLATILE SILICONE OIL AND/OR VOLATILE HYDROCARBON OIL, NON-VOLATILE OIL, PIGMENT AND ORGANIC AMPHIPHILIC MATERIAL CAPABLE OF FORMING SMECTIC LYOTROPIC LIQUID CRYSTALS IN PRODUCT OR ON THE SKIN | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| EP-0941057-A1 | COSMETIC COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1999-09-15 | — | — | EP | disclosed |
| EP-0941043-A2 | COSMETIC COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1999-09-15 | — | — | EP | disclosed |
| WO-1999038486-A1 | COSMETIC COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999038485-A1 | COSMETIC COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1998055089-A1 | COSMETIC COMPOSITIONS COMPRISING A PROTEINACEOUS MATERIAL AND A POLYOLESTER | THE PROCTER & GAMBLE COMPANY (US) | 1998-12-10 | — | — | WO | disclosed |
| WO-1998022075-A2 | COSMETIC COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-05-28 | — | — | WO | disclosed |
| WO-1998022085-A1 | COSMETIC COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-05-28 | — | — | WO | disclosed |
| EP-0706365-A4 | COSMETIC MAKE-UP COMPOSITIONS | PROCTER & GAMBLE (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1997032561-A1 | SKIN CARE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-12 | — | — | WO | disclosed |
| WO-1997032560-A1 | SKIN CARE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-12 | — | — | WO | disclosed |
| EP-0778765-A1 | COSMETIC MAKE-UP COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996011665-A1 | COSMETIC MAKE-UP COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-04-25 | — | — | WO | disclosed |
| EP-0706365-A1 | COSMETIC MAKE-UP COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |
| WO-1994028860-A1 | COSMETIC MAKE-UP COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1994-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058051-A1 | SKIN CARE COMPOSITIONS | CUTA, KRT18, POLR1C | CA2 4308/4885TLR4 916/4885RECQL 1023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.