Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GNRHR | P30968 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652938 | 0.88 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTCHRM2HTR1A | |
| SCHEMBL7656105 | 0.86 | DRD2 (0.39) | ALDH1A1LMNAMAPTCHRM2HTR1A | |
| SCHEMBL7652262 | 0.85 | NOX4 (0.45) | ALDH1A1LMNAMAPTCHRM2HTR1A | |
| SCHEMBL7653997 | 0.85 | OPRM1 (0.38) | ALDH1A1LMNAMAPTCHRM2HTR1A | |
| SCHEMBL7656700 | 0.83 | ADORA3 (0.47) | ALDH1A1ADRA1AKDM4ECYP3A4HPGD | |
| SCHEMBL7656086 | 0.83 | CTSK (0.45) | SMN1; SMN2ALDH1A1CTSKKDM4ECYP3A4 | |
| SCHEMBL7651062 | 0.81 | CA1 (0.37) | ALDH1A1NPSR1LMNAMAPTOPRM1 | |
| SCHEMBL7655384 | 0.80 | HPGD (0.43) | NPC1RAB9AALDH1A1HTR1AHTR7 | |
| SCHEMBL7652478 | 0.80 | CTSK (0.48) | GNRHRMAPTCTSKADORA3 | |
| Dimethylamine SCHEMBL7653735 | 0.80 | ALDH1A1 (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |