Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | HTR7 | P34969 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687016 | 0.76 | HTR1A (0.53) | HTR1ADRD2HTR7HTR2A | |
| SCHEMBL7685522 | 0.76 | HTR7 (0.48) | HTR1ADRD2HTR7DRD4 | |
| SCHEMBL7686952 | 0.76 | ALDH1A1 (0.51) | DRD2MAPTMEN1KMT2APOLB | |
| SCHEMBL6987487 | 0.74 | DRD2 (0.52) | HTR1ADRD2HTR7HSD17B10HTR2A | |
| SCHEMBL7683519 | 0.73 | DRD2 (0.43) | HTR1ADRD2HTR7HTR2A | |
| SCHEMBL7675521 | 0.73 | HRH4 (0.54) | HTR1ADRD2MAPTPOLBMAPK1 | |
| SCHEMBL7683751 | 0.72 | HTR1A (0.57) | HTR1ADRD2HTR7HTR2ADRD4 | |
| SCHEMBL11822964 | 0.71 | ADRA1A (0.71) | HTR1ADRD2HTR7HTR2ADRD4 | |
| SCHEMBL7684659 | 0.69 | MEN1 (0.54) | HTR1ADRD2MAPTMEN1KMT2A | |
| SCHEMBL7686047 | 0.69 | HTR1A (0.57) | HTR1ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346622-B1 | ENANTIOMORPHS AND ISOMERS | ABBOTT LABORATORIES | 2002-02-12 | — | — | US | disclosed |