Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7725794 | 0.83 | L3MBTL1 (0.38) | MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL7724618 | 0.82 | MAPT (0.38) | ALDH1A1POLBMEN1KMT2AADRB2 | |
| SCHEMBL7724398 | 0.81 | ALDH1A1 (0.41) | ALDH1A1POLBKMT2ALMNASLC6A2 | |
| SCHEMBL7724591 | 0.79 | ALOX5 (0.38) | ALDH1A1MEN1KMT2ALMNAACHE | |
| SCHEMBL7725820 | 0.78 | TSPO (0.37) | ALDH1A1SMN1; SMN2ACHE | |
| SCHEMBL7730011 | 0.77 | ATM (0.50) | ALDH1A1MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL7720015 | 0.77 | HPGD (0.43) | ALDH1A1POLBLMNATSHRTDP1 | |
| SCHEMBL7730042 | 0.76 | MMP2 (0.38) | MEN1KMT2ATSHRL3MBTL1 | |
| SCHEMBL7720010 | 0.74 | PKM (0.42) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL7724611 | 0.74 | MMP13 (0.40) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403818-B1 | ONE POT PROCESS STARTING FROM CARBONYL COMPOUND, ALCOHOL, THIOL OR AMINE, AND PROTECTED HYDROXYDICYANO COMPOUND | EISAI CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |