Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 3/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 11/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7725831 | 0.81 | FAAH (0.38) | ALDH1A1 | |
| SCHEMBL7724591 | 0.79 | ALOX5 (0.38) | ACHEALDH1A1 | |
| SCHEMBL7724597 | 0.78 | ALDH1A1 (0.35) | SMN1; SMN2ACHEALDH1A1 | |
| SCHEMBL7725794 | 0.77 | L3MBTL1 (0.38) | — | |
| SCHEMBL7730042 | 0.76 | MMP2 (0.38) | — | |
| SCHEMBL7720015 | 0.74 | HPGD (0.43) | ALDH1A1 | |
| SCHEMBL7724611 | 0.74 | MMP13 (0.40) | SMN1; SMN2HCRTR2 | |
| SCHEMBL7724618 | 0.74 | MAPT (0.38) | ALDH1A1 | |
| SCHEMBL7720010 | 0.74 | PKM (0.42) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7724398 | 0.73 | ALDH1A1 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403818-B1 | ONE POT PROCESS STARTING FROM CARBONYL COMPOUND, ALCOHOL, THIOL OR AMINE, AND PROTECTED HYDROXYDICYANO COMPOUND | EISAI CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |