Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL452775 | 0.87 | HSD11B1 (0.47) | HSD11B1HSD17B3ALDH1A1TDP1MAPT | |
| SCHEMBL7733563 | 0.86 | CA1 (0.47) | ALDH1A1LMNACA1CA2CA12 | |
| SCHEMBL7738083 | 0.84 | ALDH1A1 (0.39) | ALDH1A1POLBCA1CA2CA12 | |
| SCHEMBL7739948 | 0.82 | HSD11B1 (0.43) | HSD11B1HSD17B3ALDH1A1TDP1MAPT | |
| SCHEMBL7741652 | 0.82 | LTA4H (0.55) | ALDH1A1LMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL2966475 | 0.81 | CA2 (0.46) | HSD11B1HSD17B3ALDH1A1LMNAHTT | |
| SCHEMBL51291 | 0.80 | TSHR (0.47) | HSD11B1HSD17B3ALDH1A1LMNAHTT | |
| SCHEMBL5699281 | 0.79 | UQCRB (0.50) | HSD11B1HSD17B3ALDH1A1LMNAMAPT | |
| SCHEMBL2961941 | 0.79 | HSD11B1 (0.44) | HSD11B1HSD17B3ALDH1A1LMNAHTT | |
| SCHEMBL503481 | 0.79 | ALDH1A1 (0.42) | HSD11B1HSD17B3ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416928-B1 | HALOGENONIUM OR SULFONIUM SALTS OF SULFONATED DIPHENYLALKANE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-07-09 | — | — | US | disclosed |