SCHEMBL7733563

SCHEMBL7733563

O=S(=O)(O[I+](c1ccccc1)c1ccccc1)c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 9/20 0.47
CA2 P00918 9/20 0.47
CA9 Q16790 7/20 0.47
CA12 O43570 7/20 0.47
CA14 Q9ULX7 2/20 0.47
CALM1 P0DP23 1/20 0.40
LTA4H P09960 2/20 0.38
CA7 P43166 2/20 0.37
CA13 Q8N1Q1 1/20 0.37
PLA2G10 O15496 1/20 0.36
PLA2G2A P14555 1/20 0.36
LMNA P02545 1/20 0.36
KEAP1 Q14145 1/20 0.36
ALDH1A1 P00352 1/20 0.36
PGR P06401 1/20 0.35
CA4 P22748 2/20 0.35
CA5A P35218 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7741652 0.89 LTA4H (0.55) LTA4HLMNAALDH1A1PGRL3MBTL1
SCHEMBL7733596 0.86 HSD11B1 (0.43) CA1CA2CA9CA12CA14
SCHEMBL7738083 0.85 ALDH1A1 (0.39) CA1CA2CA9CA12CA14
SCHEMBL454458 0.84 HTR6 (0.42) CA1CA2CA9CA12CA14
SCHEMBL5403499 0.79 KMT2A (0.46) KEAP1ALDH1A1
SCHEMBL52310 0.79 VDR (0.46) CA1CA2CA9CA12CA7
SCHEMBL10492049 0.78 VDR (0.45) CA1CA2CA9CA12CA7
SCHEMBL7739940 0.77 CA12 (0.35) CA1CA2CA9CA12CA14
SCHEMBL2634850 0.77 LMNA (0.50) CA1CA2LMNAKEAP1ALDH1A1
SCHEMBL547538 0.75 PTGS2 (0.41) CA1CA2CA9KEAP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6416928-B1 HALOGENONIUM OR SULFONIUM SALTS OF SULFONATED DIPHENYLALKANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-07-09 US disclosed