SCHEMBL7741652

SCHEMBL7741652

COc1ccc([I+](OS(=O)(=O)c2ccc(Cc3ccccc3)cc2)c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.55
ALDH1A1 P00352 5/20 0.50
HTT P42858 2/20 0.46
POLB P06746 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.43
CYP19A1 P11511 1/20 0.43
MEN1 O00255 1/20 0.43
NSD2 O96028 1/20 0.43
KMT2A Q03164 1/20 0.43
TAS2R14 Q9NYV8 2/20 0.43
PTGES O14684 1/20 0.43
TAS2R8 Q9NYW2 1/20 0.43
CXCR3 P49682 1/20 0.43
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
LMNA P02545 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MMP13 P45452 2/20 0.41
MMP1 P03956 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2634850 0.89 LMNA (0.50) ALDH1A1HTTPOLBL3MBTL1LMNA
SCHEMBL7733563 0.89 CA1 (0.47) LTA4HALDH1A1L3MBTL1LMNAPGR
SCHEMBL4655792 0.87 HTT (0.45) LTA4HALDH1A1HTTPOLBL3MBTL1
SCHEMBL7738083 0.86 ALDH1A1 (0.39) LTA4HALDH1A1POLBL3MBTL1CYP19A1
SCHEMBL760069 0.85 ALDH1A1 (0.46) ALDH1A1HTTPOLBL3MBTL1LMNA
SCHEMBL7739970 0.82 MMP13 (0.43) ALDH1A1HTTL3MBTL1CYP19A1CNR1
SCHEMBL7733596 0.82 HSD11B1 (0.43) ALDH1A1HTTPOLBLMNASMN1; SMN2
SCHEMBL4655810 0.81 NOX4 (0.47) ALDH1A1HTTL3MBTL1KMT2ALMNA
SCHEMBL244142 0.79 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ALMNAEGFR
SCHEMBL3759301 0.76 ALDH1A1 (0.49) ALDH1A1HTTCNR1CNR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6416928-B1 HALOGENONIUM OR SULFONIUM SALTS OF SULFONATED DIPHENYLALKANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-07-09 US disclosed