Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Aurintricarboxylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.67 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.31 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | C9 | P02748 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | APEX1 | P27695 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aurintricarboxylic Acid SCHEMBL6158324 | 0.97 | MEN1 (0.67) | KDM4EPOLBMEN1KMT2AHPGD | |
| Aurintricarboxylic Acid SCHEMBL29450069 | 0.81 | MEN1 (1.00) | KDM4EPOLBMEN1KMT2AHPGD | |
| Aurintricarboxylic Acid SCHEMBL29353681 | 0.81 | MEN1 (1.00) | KDM4EPOLBMEN1KMT2AHPGD | |
| Aurintricarboxylic Acid SCHEMBL98495 | 0.81 | MEN1 (1.00) | KDM4EPOLBMEN1KMT2AHPGD | |
| Aurintricarboxylic Acid SCHEMBL6158321 | 0.80 | MEN1 (0.97) | KDM4EPOLBMEN1KMT2AHPGD | |
| Aurintricarboxylic Acid SCHEMBL515038 | 0.80 | MEN1 (0.97) | KDM4EPOLBMEN1KMT2AHPGD | |
| Aurintricarboxylic Acid SCHEMBL15874321 | 0.80 | MEN1 (0.97) | KDM4EPOLBMEN1KMT2AHPGD | |
| Aurintricarboxylic Acid SCHEMBL10791075 | 0.80 | MEN1 (0.97) | KDM4EPOLBMEN1KMT2AHPGD | |
| Aurintricarboxylic Acid SCHEMBL4644958 | 0.80 | MEN1 (0.97) | KDM4EPOLBMEN1KMT2AHPGD | |
| Aurintricarboxylic Acid SCHEMBL30831678 | 0.80 | MEN1 (0.97) | KDM4EPOLBMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664216-B1 | ERADICABLE GEL INK, METHODS OF ERADICATION OF THE SAME, ERADICABLE INK KIT, AND ERADICATED INK COMPLEX | SANFORD LP (US) | 2012-11-07 | — | — | EP | claimed |
| EP-1664216-A1 | ERADICABLE GEL INK, METHODS OF ERADICATION OF THE SAME, ERADICABLE INK KIT, AND ERADICATED INK COMPLEX | Sanford, L. P. (US) | 2006-06-07 | — | — | EP | claimed |
| WO-2006019672-A1 | ERADICABLE BALL-PEN INKS | SANFORD L.P. (US) | 2006-02-23 | — | — | WO | claimed |
| US-6905539-B2 | Black eradicable ink, methods of eradication of the same, eradicable ink kit, and eradicated ink complex | SANFORD L.P. (US) | 2005-06-14 | — | — | US | claimed |
| WO-2005010112-A1 | ERADICABLE GEL INK, METHODS OF ERADICATION OF THE SAME, ERADICABLE INK KIT, AND ERADICATED INK COMPLEX | SANFORD, L.P. (US) | 2005-02-03 | — | — | WO | claimed |
| US-20050011404-A1 | ERADICABLE GEL INK, METHODS OF ERADICATION OF THE SAME, ERADICABLE INK KIT, AND ERADICATED INK COMPLEX | SANFORD L.P., AN ILLINOIS CORPORATION | 2005-01-20 | — | — | US | claimed |
| US-20220340883-A1 | USE OF iNOS INHIBITORS TO INCREASE VIRAL YIELD IN CULTURE | GENZYME CORPORATION | 2022-10-27 | — | — | US | disclosed |
| US-11299715-B2 | Use of iNOS inhibitors to increase viral yield in culture | GENZYME CORPORATION (GB) | 2022-04-12 | — | — | US | disclosed |
| EP-2547311-B1 | KIT AND METHOD FOR DETECTING POROUS DENTAL HYDROXY APATITE | INCISIVE TECH PTY LTD (AU) | 2020-05-27 | — | — | EP | disclosed |
| CN-105008523-B | Use of iNOS inhibitors for increasing virus yield in culture | 建新公司 | 2020-03-27 | — | — | CN | disclosed |
| US-10589003-B2 | Methods for coating surfaces with antimicrobial agents | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-03-17 | — | — | US | disclosed |
| US-10434037-B2 | Kit and method for detecting porous dental hydroxyapatite | INCISIVE TECHNOLOGIES PTY LTD (AU) | 2019-10-08 | — | — | US | disclosed |
| EP-3521420-A1 | USE OF INOS INHIBITORS TO INCREASE VIRAL YIELD IN CULTURE | Genzyme Corporation (US) | 2019-08-07 | — | — | EP | disclosed |
| EP-0586079-B1 | Method and apparatus for preventing color bleed in a multi-ink printing system | HEWLETT PACKARD CO (US) | 1997-05-07 | — | — | EP | disclosed |
| US-5306438-A | Dielectric hydrophobic liquid carrier fluid with anionic dye particles; quick response | LORD CORPORATION (US) | 1994-04-26 | — | — | US | disclosed |
| EP-0586079-A1 | Method and apparatus for preventing color bleed in a multi-ink printing system | Hewlett-Packard Company (US) | 1994-03-09 | — | — | EP | disclosed |
| US-4362645-A | Temperature indicating compositions of matter | AKZONA, INC. (US) | 1982-12-07 | — | — | US | disclosed |
| US-4339207-A | Temperature indicating compositions of matter | AKZONA INCORPORATED (US) | 1982-07-13 | — | — | US | disclosed |
| US-4232552-A | THERMOCHROMISM, DISPOSABLE THERMOMETERS | AKZONA INCORPORATED (US) | 1980-11-11 | — | — | US | disclosed |
| US-4093557-A | QUINOMETHIDE OR OXIDIZED PHENOLIC RESIN | HERCULES INCORPORATED (US) | 1978-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10589003-B2 | Methods for coating surfaces with antimicrobial agents | CUTA, CD63, CDC37 | THRB 4713/4885CA1 2772/4885CA2 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.